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Stauprimide

3741 Datasheet / COA / SDS

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Stauprimide | CAS No. 154589-96-5 | Additional Transcription Factor Compounds
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Description: Inhibits NME2 nuclear translocation; primes ESCs for differentiation

Chemical Name: [9S-(9α,10β,11β,13α)]-N-(2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1,3-dioxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl)-N-methylbenzamide

Purity: ≥98%

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Biological Activity

Stauprimide is a small molecule that primes embryonic stem cells (ESCs) for differentiation. Interacts with NME2 and inhibits its nuclear translocation. Increases the efficiency of directed differentiation of mouse and human ESCs in vitro.

Technical Data

M.Wt:
584.62
Formula:
C35H28N4O5
Solubility:
Soluble in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
154589-96-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A small molecule primes embryonic stem cells for differentiation.
    Zhu et al.
    Cell Stem Cell., 2009;4:416

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