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Product Details
Citations (31)

Streptavidin-HRP Summary

Streptavidin-HRP is a versatile conjugate used in both in situ labeling and flow cytometric-based assays

What is Streptavidin-HRP?

Streptavidin, MW 60,000, is covalently linked to horseradish peroxidase by a modification of the periodate method with a molar enzyme/protein ratio of 2.5:1. The conjugate binds four molecules of biotin with high affinity (K d = 10-15 M-1). The conjugate is provided in liquid form with a proprietary stabilizer added, without preservative.

Product Specifications

Dilute 1:5 for use in DAB based kits or 1:75 for use in TACS Blue Label based kits.


Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended on the product label.
Store the unopened product at 2 - 8 °C. Do not use past expiration date.


For research use only. Not for diagnostic use.

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Citations for Streptavidin-HRP

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

31 Citations: Showing 1 - 10
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  1. Notch2 Blockade Mitigates Methotrexate Chemotherapy-Induced Bone Loss and Marrow Adiposity
    Authors: Y Peymanfar, YW Su, CJ Xian
    Cells, 2022;11(9):.  2022
  2. Molecular dynamics simulations and functional studies reveal that hBD-2 binds SARS-CoV-2 spike RBD and blocks viral entry into ACE2 expressing cells
    Authors: L Zhang, SK Ghosh, SC Basavaraja, J Muller-Gre, J Penfield, A Brewer, P Ramakrishn, M Buck, A Weinberg
    bioRxiv : the preprint server for biology, 2021;0(0):.  2021
  3. The Influence of an Elastase-Sensitive Complement C5 Variant on Lupus Nephritis and Its Flare
    Authors: CR Toy, H Song, HN Nagaraja, J Scott, J Greco, X Zhang, CY Yu, JA Tumlin, BH Rovin, LA Hebert, DJ Birmingham
    Kidney international reports, 2021;6(8):2105-2113.  2021
  4. Urine lipoarabinomannan in HIV uninfected, smear negative, symptomatic TB patients: effective sample pretreatment for a sensitive immunoassay and mass spectrometry
    Authors: AG Amin, P De, B Graham, RI Calderon, MF Franke, D Chatterjee
    Scientific Reports, 2021;11(1):2922.  2021
  5. Interleukin-6 controls recycling and degradation, but not internalization of its receptors
    Authors: CM Flynn, B Kespohl, T Daunke, Y Garbers, S Düsterhöft, S Rose-John, J Haybaeck, J Lokau, S Aparicio-S, C Garbers
    The Journal of Biological Chemistry, 2021;0(0):100434.  2021
  6. A Novel Follitropin Analog Inhibits Follitropin Activity In Vitro
    Authors: N Azzam, R Bar-Shalom, F Fares
    Pharmaceutics, 2021;13(3):.  2021
  7. Colonisation Factor CD0873, an Attractive Oral Vaccine Candidate against Clostridioides difficile
    Authors: C Karyal, J Hughes, ML Kelly, JC Luckett, PV Kaye, A Cockayne, NP Minton, R Griffin
    Microorganisms, 2021;9(2):.  2021
  8. Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D3 in breast cancer
    Authors: CJ Narvaez, E LaPorta, S Robilotto, J Liang, J Welsh
    Oncotarget, 2020;11(30):2889-2905.  2020
  9. An Automated, Quantitative, and Multiplexed Assay Suitable for Point-of-Care Hepatitis B Virus Diagnostics
    Authors: AW Gani, W Wei, RZ Shi, E Ng, M Nguyen, MS Chua, S So, SX Wang
    Sci Rep, 2019;9(1):15615.  2019
  10. Mycobacterium tuberculosis Lipoarabinomannan Activates Human Neutrophils via a TLR2/1 Mechanism Distinct from Pam3CSK4
    Authors: JS Hook, M Cao, K Weng, N Kinnare, JG Moreland
    J. Immunol., 2019;0(0):.  2019
  11. Fetal cytokine response to porcine reproductive and respiratory syndrome virus-2 infection
    Authors: J Alex Paste, DJ MacPhee, JCS Harding
    Cytokine, 2019;126(0):154883.  2019
  12. Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential
    Authors: D Raghunatha, PM Radford, C Gell, D Negus, C Moore, R Till, PJ Tighe, SP Wheatley, L Martinez-P, RE Sockett, J Tyson
    Sci Rep, 2019;9(1):4293.  2019
  13. A Novel Role for C5a in B-1 Cell Homeostasis
    Authors: K Bröker, J Figge, AF Magnusen, RA Manz, J Köhl, CM Karsten
    Front Immunol, 2018;9(0):258.  2018
  14. Tough Composite Hydrogels with High Loading and Local Release of Biological Drugs
    Authors: J Li, E Weber, S Guth-Gunde, M Schuleit, A Kuttler, C Halleux, N Accart, A Doelemeyer, A Basler, B Tigani, K Wuersch, M Fornaro, M Kneissel, A Stafford, BR Freedman, DJ Mooney
    Adv Healthc Mater, 2018;0(0):.  2018
  15. Galectin-9 is Critical for Mucosal Adaptive Immunity through the TH17-IgA Axis
    Authors: CC Liang, CS Li, IC Weng, HY Chen, HH Lu, CC Huang, FT Liu
    Am. J. Pathol., 2018;0(0):.  2018
  16. Absence of a neutralizing antibody response to humanized cobra venom factor in mice
    Authors: M Ing, BE Hew, DC Fritzinger, S Delignat, S Lacroix-De, CW Vogel, J Rayes
    Mol. Immunol., 2018;97(0):1-7.  2018
  17. Biphasic Scaffolds from Marine Collagens for Regeneration of Osteochondral Defects
    Authors: A Bernhardt, B Paul, M Gelinsky
    Mar Drugs, 2018;16(3):.  2018
  18. Extending the functional characteristics of naturally occurring autoantibodies against ?-Amyloid, Prion Protein and ?-Synuclein
    Authors: A Albus, M Gold, JP Bach, M Burg-Roder, M Jördens, Y Kirchhein, Y Kronimus, D Mengel, I Zerr, R Dodel
    PLoS ONE, 2018;13(8):e0202954.  2018
  19. Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers
    Authors: Y Aldon, PF McKay, J Allen, G Ozorowski, R Felfödiné, M Tolazzi, P Rogers, L He, N de Val, K Fábián, G Scarlatti, J Zhu, AB Ward, M Crispin, RJ Shattock
    Cell Rep, 2018;24(12):3324-3338.e5.  2018
  20. Prominent Levels of the Profibrotic Chemokine CCL18 during Peritonitis: In Vitro Downregulation by Vitamin D Receptor Agonists
    Authors: M Ossorio, V Martínez, MA Bajo, G Del Peso, MJ Castro, S Romero, R Selgas, T Bellón
    Biomed Res Int, 2018;2018(0):6415892.  2018
  21. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies
    Authors: Mihalis S Kariolis
    J. Clin. Invest, 2016;0(0):.  2016
  22. Autophagy in Dendritic Cells and B Cells Is Critical for the Inflammatory State of TLR7-Mediated Autoimmunity
    Authors: Chi G Weindel
    J. Immunol, 2016;0(0):.  2016
  23. Bortezomib treatment diminishes hazelnut-induced intestinal anaphylaxis in mice
    Authors: KK Mudnakudu, M Babina, C Weise, A Kühl, J Schulzke, M Worm
    Eur J Immunol, 2016;0(0):.  2016
  24. DSGOST inhibits tumor growth by blocking VEGF/VEGFR2-activated angiogenesis
    Oncotarget, 2016;7(16):21775-85.  2016
  25. Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17
    Sci Rep, 2016;6(0):25550.  2016
  26. Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation.
    Authors: Foo, Suan-Sin, Chen, Weiqiang, Taylor, Adam, Sheng, Kuo-Chin, Yu, Xing, Teng, Terk-Shi, Reading, Patrick, Blanchard, Helen, Garlanda, Cecilia, Mantovani, Alberto, Ng, Lisa F P, Herrero, Lara J, Mahalingam, Suresh
    PLoS Pathog, 2015;11(2):e1004649.  2015
  27. A tool kit for rapid cloning and expression of recombinant antibodies.
    Authors: Dodev T, Karagiannis P, Gilbert A, Josephs D, Bowen H, James L, Bax H, Beavil R, Pang M, Gould H, Karagiannis S, Beavil A
    Sci Rep, 2014;4(0):5885.  2014
  28. Serum amino acids profile and the beneficial effects of L-arginine or L-glutamine supplementation in dextran sulfate sodium colitis.
    Authors: Ren W, Yin J, Wu M, Liu G, Yang G, Xion Y, Su D, Wu L, Li T, Chen S, Duan J, Yin Y, Wu G
    PLoS ONE, 2014;9(2):e88335.  2014
  29. Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a).
    Authors: Leibundgut G, Scipione C, Yin H, Schneider M, Boffa M, Green S, Yang X, Dennis E, Witztum J, Koschinsky M, Tsimikas S
    J Lipid Res, 2013;54(10):2815-30.  2013
  30. Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis.
    Authors: Palmer G, Talabot-Ayer D, Lamacchia C, Toy D, Seemayer CA, Viatte S, Finckh A, Smith DE, Gabay C
    Arthritis Rheum., 2009;60(3):738-49.  2009
  31. A role for calcium-calmodulin in regulating nitric oxide production during skeletal muscle satellite cell activation.
    Authors: Tatsumi R, Wuollet AL, Tabata K, Nishimura S, Tabata S, Mizunoya W, Ikeuchi Y, Allen RE
    Am. J. Physiol., Cell Physiol., 2009;296(4):C922-9.  2009


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