Catalog Number: 0731
Chemical Name: 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide
Biological Activity
A selective ETA endothelin receptor antagonist (IC50 values are 600 and 2200 nM for ETA and ETB receptors respectively).
Technical Data
  • M.Wt:
    267.3
  • Formula:
    C11H13N3O3S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    127-69-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Identification of a new class of ETA selective endothelin antagonists by pharmacophore directed screening.
    Chan et al.
    Biochem.Biophys.Res.Commun., 1994;201:228

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