Synapsin I [p Ser9] Antibody (SR2212) - BSA Free

Novus Biologicals | Catalog # NBP3-21540

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2212 expressed in HEK293

Format

BSA Free
View all Synapsin I Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human phospho-Synapsin I [Ser9] (Uniprot #: P17600)

Modification

p Ser 9

Specificity

Detects endogenous levels of phospho-Synapsin I [Ser9]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

77 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Synapsin I [p Ser9] Antibody (SR2212) - BSA Free

Western Blot: Synapsin I [p Ser 9] Antibody (SR2212) [NBP3-21540] -

Western Blot: Synapsin I [p Ser 9] Antibody (SR2212) [NBP3-21540] - Western blot analysis using NBP3-21540 in (1) Human brain lysate; (2) Human brain lysate treated with AP.

Applications for Synapsin I [p Ser9] Antibody (SR2212) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Synapsin I

Synapsin I is a neuron specific protein that is localized to nerve terminals. Synapsin Ia and Synapsin Ib are approximately 80,000 and 77,000 Daltons, respectively, and are collectively referred to as synapsin I. The synapsin protein is an excellent marker for synaptic terminals and it can be used to estimate synaptic density and or synaptogenesis. It is thought that synapsin I cross-links synaptic vesicles to the cytoskeleton and thereby limits the ability of these synaptic vesicles to move to active zones and fuse with the plasma membrane during exocytosis. In addition to their role in neurotransmission, the synapsins are also thought to play a role in synapse formation. The appearance of synapsin I immunoreactivity correlates precisely with the development of synapses in the CNS. The synapsin protein is an excellent marker for synaptic terminals and it can be used to estimate synaptic density and or synaptogenesis. The appearance of synapsin I was a precise indicator of synapse formation and that synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis.

Alternate Names

SYN1

Gene Symbol

SYN1

Additional Synapsin I Products

Product Documents for Synapsin I [p Ser9] Antibody (SR2212) - BSA Free

Certificate of Analysis

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Product Specific Notices for Synapsin I [p Ser9] Antibody (SR2212) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Neuronal Markers

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Protocols

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