Catalog Number: 0635
Chemical Name: N,N'-1,10-Decanediylbisguanidine sulfate
Biological Activity
An effective non-competitive NMDA receptor antagonist in vivo and in vitro; may bind to more than one site, one of which is the polyamine site.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 5 mM in water
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Interactions between zinc and spermidine on the N-methyl-D-aspartate receptor complex: clues to the mechanism of action of 1,10-bis(guanidino)decane and pentamidine.
    J.Pharmacol.Exp.Ther., 1992;263:632
  2. 1,10-Bis(guanidino)decane inhibits N-methyl-D-aspartate responses in vitro and in vivo.
    Reynolds et al.
    J.Pharmacol.Exp.Ther., 1991;259:626

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