Synthalin sulfate

Name: Synthalin sulfate
Brand: Tocris Bioscience
SKU: 0635

Catalog #: 0635 Datasheet / COA / SDS

Discontinued Product

0635 has been discontinued.

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Synthalin sulfate | CAS No. 182285-12-7 | NMDA Receptor Antagonists

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Description: Non-competitive NMDA antagonist

Chemical Name: N,N'-1,10-Decanediylbisguanidine sulfate

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Product Details

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Biological Activity

An effective non-competitive NMDA receptor antagonist in vivo and in vitro; may bind to more than one site, one of which is the polyamine site.

Technical Data

M.Wt:

354.47

Formula:

C₁₂H₂₈N₆.H₂SO₄

Solubility:

Soluble to 5 mM in water

Storage:

Store at RT

CAS No:

182285-12-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1,10-Bis(guanidino)decane inhibits N-MthD.-aspartate responses in vitro and in vivo.
Reynolds et al.
J.Pharmacol.Exp.Ther., 1991;259:626
Interactions between zinc and spermidine on the N-MthD.-aspartate receptor complex: clues to the mechanism of action of 1,10-bis(guanidino)decane and pentam.
Reynolds
J.Pharmacol.Exp.Ther., 1992;263:632

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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