TACS 2 TdT-DAB In Situ Apoptosis Detection Kit

Preferable Transplant Site for Hepatocyte Transplantation in a Rat Model
Authors: H Ogasawara, A Inagaki, I Fathi, T Imura, H Yamana, Y Saitoh, M Matsumura, K Fukuoka, S Miyagi, Y Nakamura, K Ohashi, M Unno, T Kamei, M Goto
Cell Transplantation, 2021;30(0):9636897211040.  2021

SIRT6?specific inhibitor OSS?128167 exacerbates diabetic cardiomyopathy by aggravating inflammation and oxidative stress
Authors: Y Huang, J Zhang, D Xu, Y Peng, Y Jin, L Zhang
Molecular Medicine Reports, 2021;23(5):.  2021

Reduced hyaluronan cross-linking induces breast cancer malignancy in a CAF-dependent manner
Authors: G Zhang, Y He, Y Liu, Y Du, C Yang, F Gao
Cell Death & Disease, 2021;12(6):586.  2021

Inhibition of NLRP3 inflammasome by MCC950 improves the metabolic outcome of islet transplantation by suppressing IL-1&beta and islet cellular death
Authors: T Matsuoka, G Yoshimatsu, N Sakata, R Kawakami, T Tanaka, T Yamada, Y Yoshida, S Hasegawa, S Kodama
Sci Rep, 2020;10(1):17920.  2020

Targeting alkaline ceramidase 3 alleviates the severity of nonalcoholic steatohepatitis by reducing oxidative stress
Authors: K Wang, C Li, X Lin, H Sun, R Xu, Q Li, Y Wei, Y Li, J Qian, C Liu, Q Zhang, S Yu, Z Cui, X Huang, B Zhu, J Zhou, C Mao
Cell Death Dis, 2020;11(1):28.  2020

Mast4 knockout shows the regulation of spermatogonial stem cell self-renewal via the FGF2/ERM pathway
Authors: SJ Lee, J Park, DJ Lee, K Otsu, P Kim, S Mizuno, MJ Lee, HY Kim, H Harada, S Takahashi, SJ Kim, HS Jung
Cell Death Differ, 2020;0(0):.  2020

Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis
Authors: Y Takagaki, SM Lee, Z Dongqing, M Kitada, K Kanasaki, D Koya
Autophagy, 2020;0(0):1-10.  2020

Compensatory combination of romidepsin with gemcitabine and cisplatin to effectively and safely control urothelial carcinoma
Authors: P Pattarawat, T Hong, S Wallace, Y Hu, R Donnell, TH Wang, CL Tsai, J Wang, HR Wang
Br. J. Cancer, 2020;0(0):.  2020

Spred2-deficiency enhances the proliferation of lung epithelial cells and alleviates pulmonary fibrosis induced by bleomycin
Authors: A Kawara, R Mizuta, M Fujisawa, T Ito, C Li, K Nakamura, C Sun, M Kuwabara, M Kitabatake, T Yoshimura, A Matsukawa
Sci Rep, 2020;10(1):16490.  2020

Periadventitial Delivery of Simvastatin-Loaded Microparticles Attenuate Venous Neointimal Hyperplasia Associated With Arteriovenous Fistula
Authors: C Zhao, ST Zuckerman, C Cai, S Kilari, A Singh, M Simeon, HA von Recum, JN Korley, S Misra
Journal of the American Heart Association, 2020;9(24):e018418.  2020

NF-kappaB inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-kappaB(p65) and actin cytoskeleton regulatory pathways
Authors: NG Avci, S Ebrahimzad, YM Akay, Y Esquenazi, N Tandon, JJ Zhu, M Akay
Sci Rep, 2020;10(1):13352.  2020

Enhanced Biocompatibility of Multi-Layered, 3D Bio-Printed Artificial Vessels Composed of Autologous Mesenchymal Stem Cells
Authors: EH Jang, JH Kim, JH Lee, DH Kim, YN Youn
Polymers (Basel), 2020;12(3):.  2020

Attenuation of diabetic cardiomyopathy by relying on kirenol to suppress inflammation in a diabetic rat model
Authors: B Wu, XY Huang, L Li, XH Fan, PC Li, CQ Huang, J Xiao, R Gui, S Wang
J. Cell. Mol. Med., 2019;0(0):.  2019

Inhibitor of DNA-Binding Protein 4 Suppresses Cancer Metastasis through the Regulation of Epithelial Mesenchymal Transition in Lung Adenocarcinoma
Authors: CC Wang, YL Hsu, CJ Chang, CJ Wang, TH Hsiao, SH Pan
Cancers (Basel), 2019;11(12):.  2019

Triptolide sensitizes cisplatin-resistant human epithelial ovarian cancer by inhibiting the phosphorylation of AKT
Authors: G Huang, H Hu, Y Zhang, Y Zhu, J Liu, B Tan, T Chen
J Cancer, 2019;10(13):3012-3020.  2019

Zika virus infection at mid-gestation results in fetal cerebral cortical injury and fetal death in the olive baboon
Authors: S Gurung, N Reuter, A Preno, J Dubaut, H Nadeau, K Hyatt, K Singleton, A Martin, WT Parks, JF Papin, DA Myers
PLoS Pathog., 2019;15(1):e1007507.  2019

MiR-30c/PGC-1? protects against diabetic cardiomyopathy via PPAR?
Authors: Z Yin, Y Zhao, M He, H Li, J Fan, X Nie, M Yan, C Chen, DW Wang
Cardiovasc Diabetol, 2019;18(1):7.  2019

Epithelial ovarian cancer: feasibility of image-guided intratumoral radiofrequency hyperthermia-enhanced direct gene therapy
Authors: G Jin, Y Li, F Zhang, P Li, L Zhao, Y Zhou, H Ji, S Pietrini, B Zhai, X Yang
Am J Cancer Res, 2019;9(2):378-389.  2019

Impaired LXR? Phosphorylation Attenuates Progression of Fatty Liver Disease
Authors: N Becares, MC Gage, M Voisin, E Shrestha, L Martin-Gut, N Liang, R Louie, B Pourcet, OM Pello, TV Luong, S Goñi, C Pichardo-A, H Røberg-Lar, V Diaz-Zucca, KR Steffensen, A O'Brien, MJ Garabedian, K Rombouts, E Treuter, I Pineda-Tor
Cell Rep, 2019;26(4):984-995.e6.  2019

A Simple and Useful Predictive Assay for Evaluating the Quality of Isolated Hepatocytes for Hepatocyte Transplantation
Authors: M Matsumura, T Imura, A Inagaki, H Ogasawara, K Fukuoka, I Fathi, S Miyagi, K Ohashi, M Unno, T Kamei, S Satomi, M Goto
Sci Rep, 2019;9(1):6166.  2019

8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes
Authors: N Haruyama, K Sakumi, A Katogi, D Tsuchimoto, G De Luca, M Bignami, Y Nakabeppu
Prog. Neurobiol., 2019;0(0):.  2019

Schwannoma gene therapy by adeno-associated virus delivery of the pore-forming protein Gasdermin-D
Authors: SG Ahmed, A Ahmed, M Doha, GJ Brenner
Cancer Gene Ther., 2019;0(0):.  2019

VEGF-A from Granuloma Macrophages Regulates Granulomatous Inflammation by a Non-angiogenic Pathway during Mycobacterial Infection
Authors: JS Harding, M Herbath, Y Chen, A Rayasam, A Ritter, B Csoka, G Hasko, IP Michael, Z Fabry, A Nagy, M Sandor
Cell Rep, 2019;27(7):2119-2131.e6.  2019

Concomitant Inhibition of Cytoprotective Autophagy Augments the Efficacy of Withaferin A in Hepatocellular Carcinoma
Authors: S Siddharth, N Muniraj, NK Saxena, D Sharma
Cancers (Basel), 2019;11(4):.  2019

Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines
Authors: BE Dawes, J Gao, C Atkins, JT Nelson, K Johnson, P Wu, AN Freiberg
J Neuroinflammation, 2018;15(1):315.  2018

Cardioprotective Effects of QiShenYiQi Dripping Pills on Transverse Aortic Constriction-Induced Heart Failure in Mice
Authors: G Ruan, H Ren, C Zhang, X Zhu, C Xu, L Wang
Front Physiol, 2018;9(0):324.  2018

Role of SIRT2 in Regulation of Stemness of Cancer Stem-Like Cells in Renal Cell Carcinoma
Authors: R Wei, D He, X Zhang
Cell. Physiol. Biochem., 2018;49(6):2348-2357.  2018

Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein
Authors: L Aumailley, MJ Dubois, TA Brennan, C Garand, ER Paquet, RJ Pignolo, A Marette, M Lebel
FASEB J., 2018;0(0):fj201701176R.  2018

RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction
Authors: A Sureshbabu, E Patino, KC Ma, K Laursen, EJ Finkelszte, O Akchurin, T Muthukumar, SW Ryter, L Gudas, AMK Choi, ME Choi
JCI Insight, 2018;3(11):.  2018

Treatment of Arsenite Intoxication-Induced Peripheral Vasculopathy with Mesenchymal Stem Cells
Authors: YH Chiang, CC Lin, YC Chen, OK Lee
Int J Mol Sci, 2018;19(4):.  2018

X-linked inhibitor of apoptosis inhibition sensitizes acute myeloid leukemia cell response to TRAIL and chemotherapy through potentiated induction of proapoptotic machinery
Authors: J Zhou, X Lu, TZ Tan, WJ Chng
Mol Oncol, 2018;12(1):33-47.  2018

Concomitant modulation of PTEN and Livin in gastric cancer treatment
Authors: CL Zhao, SN Han, ZJ Wang, SH Wang, GQ Zhao, XF Zhang, JX Wang
Int. J. Mol. Med., 2018;0(0):.  2018

Chronic PARP-1 inhibition reduces carotid vessel remodeling and oxidative damage of the dorsal hippocampus in spontaneously hypertensive rats
Authors: K Eros, K Magyar, L Deres, A Skazel, A Riba, Z Vamos, T Kalai, F Gallyas, B Sumegi, K Toth, R Halmosi
PLoS ONE, 2017;12(3):e0174401.  2017

Calcium-dependent enhancement by extracellular acidity of the cytotoxicity of mitochondrial inhibitors against melanoma
Authors: F Noguchi, S Inui, C Fedele, M Shackleton, S Itami
Mol. Cancer Ther, 2017;0(0):.  2017

Histone demethylase PHF8 accelerates the progression of colorectal cancer and can be regulated by miR-488 in�vitro
Authors: Y Lv, Y Shi, Q Han, G Dai
Mol Med Rep, 2017;16(4):4437-4444.  2017

Influence of long-term, high-dose dexamethasone administration on proliferation and apoptosis in porcine hepatocytes
Authors: M Mikiewicz, I Otrocka-Do, K Pa?dzior-C, T Rotkiewicz
Res. Vet. Sci., 2017;112(0):141-148.  2017

Chromatin assembly factor 1, subunit A (P150) facilitates cell proliferation in human hepatocellular carcinoma
Onco Targets Ther, 2016;9(0):4023-35.  2016

PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma
PLoS Genet, 2016;12(12):e1006518.  2016

Granzyme B Deficiency Protects against Angiotensin II-Induced Cardiac Fibrosis.
Authors: Shen Y, Cheng F, Sharma M, Merkulova Y, Raithatha S, Parkinson L, Zhao H, Westendorf K, Bohunek L, Bozin T, Hsu I, Ang L, Williams S, Bleackley R, Eriksson J, Seidman M, McManus B, Granville D
Am J Pathol, 2016;186(1):87-100.  2016

FBXW7 acts as an independent prognostic marker and inhibits tumor growth in human osteosarcoma.
Authors: Li, Zhanchun, Xiao, Jie, Hu, Kongzu, Wang, Gang, Li, Maoqiang, Zhang, Jidong, Cheng, Guangqi
Int J Mol Sci, 2015;16(2):2294-306.  2015

Immunosuppression abrogates resistance of young rabbits to Rabbit Haemorrhagic Disease (RHD).
Authors: Marques R, Teixeira L, Aguas A, Ribeiro J, Costa-e-Silva A, Ferreira P
Vet Res, 2014;45(0):14.  2014

Inhibition of JNK phosphorylation by a novel curcumin analog prevents high glucose-induced inflammation and apoptosis in cardiomyocytes and the development of diabetic cardiomyopathy.
Authors: Pan Y, Wang Y, Zhao Y, Peng K, Li W, Wang Y, Zhang J, Zhou S, Liu Q, Li X, Cai L, Liang G
Diabetes, 2014;63(10):3497-511.  2014

Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma.
Authors: Tu, Kangshen, Yang, Wei, Li, Chao, Zheng, Xin, Lu, Zhongtan, Guo, Cheng, Yao, Yingmin, Liu, Qingguan
Mol Cancer, 2014;13(0):110.  2014

Biomimetic scaffold combined with electrical stimulation and growth factor promotes tissue engineered cardiac development.
Authors: Park H, Larson B, Kolewe M, Vunjak-Novakovic G, Freed L
Exp Cell Res, 2014;321(2):297-306.  2014

Prognostic significance of miR-218 in human hepatocellular carcinoma and its role in cell growth.
Authors: Tu K, Li C, Zheng X, Yang W, Yao Y, Liu Q
Oncol Rep, 2014;32(4):1571-7.  2014

Role of leukotriene A4 hydrolase aminopeptidase in the pathogenesis of emphysema.
Authors: Paige M, Wang K, Burdick M, Park S, Cha J, Jeffery E, Sherman N, Shim Y
J Immunol, 2014;192(11):5059-68.  2014

Mebendazole reduces vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice.
Authors: Wang J, Wang H, Guo C, Luo W, Lawler A, Reddy A, Wang J, Sun E, Eitzman D
PLoS ONE, 2014;9(2):e90146.  2014

Increased chondrocyte apoptosis is associated with progression of osteoarthritis in spontaneous Guinea pig models of the disease.
Authors: Zamli Z, Adams M, Tarlton J, Sharif M
Int J Mol Sci, 2013;14(9):17729-43.  2013

The alternative complement pathway propagates inflammation and injury in murine ischemic stroke.
Authors: Elvington, Andrew, Atkinson, Carl, Zhu, Hong, Yu, Jin, Takahashi, Kazue, Stahl, Gregory, Kindy, Mark S, Tomlinson, Stephen
J Immunol, 2012;189(9):4640-7.  2012

Posthatch development of the axial musculature of the common dentex Dentex dentex, L (Teleostei).
Histol. Histopathol., 2010;25(0):1557-71.  2010

Cryopreservation Method for the Effective Collection of Dental Pulp Stem Cells.
Authors: Takebe Y, Tatehara S, Fukushima T, Tokuyama-Toda R, Yasuhara R, Mishima K, Satomura K
Tissue Eng Part C Methods, 0;23(5):251-261.  0

Experimental mild renal insufficiency mediates early cardiac apoptosis, fibrosis, and diastolic dysfunction: a kidney-heart connection.
Authors: Martin F, McKie P, Cataliotti A, Sangaralingham S, Korinek J, Huntley B, Oehler E, Harders G, Ichiki T, Mangiafico S, Nath K, Redfield M, Chen H, Burnett J
Am J Physiol Regul Integr Comp Physiol, 0;302(2):R292-9.  0

Adipocyte hypertrophy is associated with lysosomal permeability both in vivo and in vitro: role in adipose tissue inflammation.
Authors: Gornicka A, Fettig J, Eguchi A, Berk M, Thapaliya S, Dixon L, Feldstein A
Am J Physiol Endocrinol Metab, 0;303(5):E597-606.  0

Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells.
Authors: Li J, Csibi A, Yang S, Hoffman G, Li C, Zhang E, Yu J, Blenis J
Proc Natl Acad Sci U S A, 0;112(1):E21-9.  0

ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death.
Authors: Lhotak S, Sood S, Brimble E, Carlisle R, Colgan S, Mazzetti A, Dickhout J, Ingram A, Austin R
Am J Physiol Renal Physiol, 0;303(2):F266-78.  0

Uterine natural killer cell partnerships in early mouse decidua basalis.
Authors: Felker A, Croy B
J Leukoc Biol, 0;100(4):645-655.  0

IL-13 immunotoxin accelerates resolution of lung pathological changes triggered by silica particles in mice.
Authors: Ferreira T, de Arantes A, do Nascimento C, Olsen P, Trentin P, Rocco P, Hogaboam C, Puri R, Martins M, Silva P
J Immunol, 0;191(10):5220-9.  0

The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a cxcl signaling module.
Authors: Chen K, Wu K, Jiao X, Wang L, Ju X, Wang M, Di Sante G, Xu S, Wang Q, Li K, Sun X, Xu C, Li Z, Casimiro M, Ertel A, Addya S, McCue P, Lisanti M, Wang C, Davis R, Mardon G, Pestell R
Cancer Res, 0;75(10):1992-2004.  0

Tumor promoter-induced sulfiredoxin is required for mouse skin tumorigenesis.
Authors: Wu L, Jiang H, Chawsheen H, Mishra M, Young M, Gerard M, Toledano M, Colburn N, Wei Q
Carcinogenesis, 0;35(5):1177-84.  0

Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma.
Authors: Kephart J, Tiller R, Crose L, Slemmons K, Chen P, Hinson A, Bentley R, Chi J, Linardic C
Clin Cancer Res, 0;21(21):4868-80.  0

Vanadium toxicity in mice: possible impairment of lipid metabolism and mucosal epithelial cell necrosis in the small intestine.
Authors: Imura H, Shimada A, Naota M, Morita T, Togawa M, Hasegawa T, Seko Y
Toxicol Pathol, 0;41(6):842-56.  0

ENOblock, a unique small molecule inhibitor of the non-glycolytic functions of enolase, alleviates the symptoms of type 2 diabetes.
Authors: Cho H, Um J, Lee J, Kim W, Kang W, Kim S, Ha H, Kim Y, Ahn Y, Jung D, Williams D
Sci Rep, 0;7(0):44186.  0

Reduction of Na/K-ATPase affects cardiac remodeling and increases c-kit cell abundance in partial nephrectomized mice.
Authors: Drummond C, Sayed M, Evans K, Shi H, Wang X, Haller S, Liu J, Cooper C, Xie Z, Shapiro J, Tian J
Am J Physiol Heart Circ Physiol, 0;306(12):H1631-43.  0

Regulation of Sirtuin 3-Mediated Deacetylation of Cyclophilin D Attenuated Cognitive Dysfunction Induced by Sepsis-Associated Encephalopathy in Mice.
Authors: Sun F, Si Y, Bao H, Xu Y, Pan X, Zeng L, Jing L
Cell Mol Neurobiol, 0;37(8):1457-1464.  0

Differential cell-matrix responses in hypoxia-stimulated aortic versus mitral valves.
Authors: Sapp M, Krishnamurthy V, Puperi D, Bhatnagar S, Fatora G, Mutyala N, Grande-Allen K
J R Soc Interface, 0;13(125):.  0

Reovirus uses multiple endocytic pathways for cell entry.
Authors: Schulz W, Haj A, Schiff L
J Virol, 0;86(23):12665-75.  0

Distinct Immune Responses in Resistant and Susceptible Strains of Mice during Neurovirulent Alphavirus Encephalomyelitis.
Authors: Kulcsar K, Baxter V, Abraham R, Nelson A, Griffin D
J Virol, 0;89(16):8280-91.  0

Bacterial chemotaxis modulates host cell apoptosis to establish a T-helper cell, type 17 (Th17)-dominant immune response in Helicobacter pylori infection.
Authors: Rolig A, Carter J, Ottemann K
Proc Natl Acad Sci U S A, 0;108(49):19749-54.  0

Smpd3 Expression in both Chondrocytes and Osteoblasts Is Required for Normal Endochondral Bone Development.
Authors: Li J, Manickam G, Ray S, Oh C, Yasuda H, Moffatt P, Murshed M
Mol Cell Biol, 0;36(17):2282-99.  0

Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer.
Authors: Straume O, Shimamura T, Lampa M, Carretero J, Oyan A, Jia D, Borgman C, Soucheray M, Downing S, Short S, Kang S, Wang S, Chen L, Collett K, Bachmann I, Wong K, Shapiro G, Kalland K, Folkman J, Watnick R, Akslen L, Naumov G
Proc Natl Acad Sci U S A, 0;109(22):8699-704.  0

Neonatal uterine and vaginal cell proliferation and adenogenesis are independent of estrogen receptor 1 (ESR1) in the mouse.
Authors: Nanjappa M, Medrano T, March A, Cooke P
Biol Reprod, 0;92(3):78.  0

Transient increase of fractional anisotropy in reversible vasogenic edema.
Authors: Kimura-Ohba S, Yang Y, Thompson J, Kimura T, Salayandia V, Cosse M, Yang Y, Sillerud L, Rosenberg G
J Cereb Blood Flow Metab, 0;36(10):1731-1743.  0

Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis.
Authors: Roulis M, Nikolaou C, Kotsaki E, Kaffe E, Karagianni N, Koliaraki V, Salpea K, Ragoussis J, Aidinis V, Martini E, Becker C, Herschman H, Vetrano S, Danese S, Kollias G
Proc Natl Acad Sci U S A, 0;111(43):E4658-67.  0

TLR4 Deficiency Impairs Oligodendrocyte Formation in the Injured Spinal Cord.
Authors: Church J, Kigerl K, Lerch J, Popovich P, McTigue D
J Neurosci, 0;36(23):6352-64.  0

Targeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer.
Authors: Davidson L, Callaway E, Kim E, Weeks B, Fan Y, Allred C, Chapkin R
Cancer Res, 0;75(24):5392-7.  0

mTORC1-Driven Tumor Cells Are Highly Sensitive to Therapeutic Targeting by Antagonists of Oxidative Stress.
Authors: Li J, Shin S, Sun Y, Yoon S, Li C, Zhang E, Yu J, Zhang J, Blenis J
Cancer Res, 0;76(16):4816-27.  0

Folate Receptor-Targeted Polymeric Micellar Nanocarriers for Delivery of Orlistat as a Repurposed Drug against Triple-Negative Breast Cancer.
Authors: Paulmurugan R, Bhethanabotla R, Mishra K, Devulapally R, Foygel K, Sekar T, Ananta J, Massoud T, Joy A
Mol Cancer Ther, 0;15(2):221-31.  0

Acceleration of diabetic wound healing using a novel protease-anti-protease combination therapy.
Authors: Gao M, Nguyen T, Suckow M, Wolter W, Gooyit M, Mobashery S, Chang M
Proc Natl Acad Sci U S A, 0;112(49):15226-31.  0