TAS 301
Chemical Name: 3-[Bis(4-methoxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one
Purity: ≥99%
Biological Activity
TAS 301 is an inhibitor of smooth muscle cell migration and proliferation. Blocks voltage-independent calcium influx and downstream PKC signaling. Inhibits neointimal thickening after balloon catheter injury to the rat common carotid artery.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.
Muranaka et al.
J.Pharmacol.Exp.Ther., 1998;285:1280 -
TAS-301 blocks receptor-operated calcium influx and inhibits rat vascular smooth muscle cell proliferation induced by basic fibroblast growth factor and platelet-derived growth factor.
Sasaki et al.
Jpn.J.Pharmacol., 2000;84:252
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for TAS 301
There are currently no reviews for this product. Be the first to review TAS 301 and earn rewards!
Have you used TAS 301?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
