Catalog Number: 2825
Chemical Name: (2E)-3-(2,3,4,5-Tetrabromophenyl)-2-propenoic acid
Biological Activity
Selective CK2 inhibitor (IC50 = 110 nM). Exhibits selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases. Reduces viability of Jurkat cells in vitro.
Technical Data
  • M.Wt:
    463.74
  • Formula:
    C9H4Br4O2
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    934358-00-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors.
    Pagano et al.
    Chembiochem., 2007;8:129
Citations:

The citations listed below are publications that use Tocris products. Selected citations for TBCA include:

1 Citations: Showing 1 - 1

  1. Acupuncture elicits neuroprotective effect by inhibiting NAPDH oxidase-mediated reactive oxygen species production in cerebral ischaemia.
    Authors: Shi Et al.
    J Virol 2015;5:17981

Have you used TBCA?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Feedback

Customer Information