Home / Aurora Kinase Inhibitors / TC-S 7010

TC-S 7010

Catalog #: 5286 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5286/10
5286/50
TC-S 7010 | CAS No. 1158838-45-9 | Aurora Kinase Inhibitors
1 Image
Description: Potent and selective Aurora kinase A inhibitor

Chemical Name: N-(2-Chlorophenyl)-4-[[2-[[4-[2-(4-ethyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-benzamide

Purity: ≥99%

Product Details
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

TC-S 7010 is a potent and selective inhibitor of Aurora kinase A (IC50 = 3.4 nM); exhibits 1000-fold selectivity for Aurora kinase A over Aurora kinase B. Displays antiproliferative activity in HCT116 and HT29 cells (IC50 values are 0.19 and 2.9 μM respectively).

Technical Data

M.Wt:
588.07
Formula:
C31H31ClFN7O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
1158838-45-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Complete Your Research

Lysine acetyltransferase HBO1 (KAT7) inhibitor
Cat # 7366
Nur77 agonist; induces autophagy in melanoma cell lines
Cat # 6017
Selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator
Cat # 6887
Potent and selective noradrenalin re-uptake inhibitor
Cat # 2011
HIV-1 and HIV-2 protease inhibitor
Cat # 5856
Positive allosteric modulator of KCa3.1 (IK) channels
Cat # 6398
Mixed mGlu2 agonist/ mGlu3 antagonist
Cat # 3272
Potent and selective PI 3-Kβ inhibitor
Cat # 4839
Selective SIRT2 inhibitor; brain penetrant
Cat # 4754
Potent negative modulator of KCa2.3 and KCa3.1 channels
Cat # 7129
Selective α4β2 nAChR partial agonist
Cat # 2737
Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II
Cat # 3260
Potent and high affinity H2 biased inverse agonist
Cat # 7290
STING antagonist
Cat # 6675
Potent and selective LXR inverse agonist
Cat # 5854
Positive allosteric modulator of GABAA receptors; direct agonist at higher concentrations
Cat # 2738
Selective positive allosteric modulator of mGlu2 receptors
Cat # 3283
Inhibitor of γ-secretase-mediated βAPP processing
Cat # 2677

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for TC-S 7010

There are currently no reviews for this product. Be the first to review TC-S 7010 and earn rewards!

Have you used TC-S 7010?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.