Catalog Number: 5100
Chemical Name: 2,2'-[[4,8-Bis[bis(2-methylpropyl)amino]pyrimido[5,4-d]pyrimidine-2,6-diyl]diimino]bis-ethanol
Biological Activity
Potent equilibrative nucleoside transporter 4 (ENT4) inhibitor (IC50 = 74.4 nM). Exhibits 20-fold and 80-fold selectivity for ENT4 over ENT2 and ENT1, respectively.
Technical Data
  • M.Wt:
    504.71
  • Formula:
    C26H48N8O2
  • Solubility:
    Soluble to 20 mM in DMSO and to 20 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at RT
  • CAS No:
    949467-71-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4).
    Wang et al.
    Biochem.Pharmacol., 2013;86:1531

Have you used TC-T 6000?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Feedback

Customer Information