Catalog Number: 5100
Chemical Name: 2,2'-[[4,8-Bis[bis(2-methylpropyl)amino]pyrimido[5,4-d]pyrimidine-2,6-diyl]diimino]bis-ethanol
Biological Activity
Potent equilibrative nucleoside transporter 4 (ENT4) inhibitor (IC50 = 74.4 nM). Exhibits 20-fold and 80-fold selectivity for ENT4 over ENT2 and ENT1, respectively.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 20 mM in DMSO and to 20 mM in ethanol
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4).
    Wang et al.
    Biochem.Pharmacol., 2013;86:1531
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