TEP1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-42356

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Format

BSA Free
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Product Specifications

Immunogen

Immunogen sequence: Glu2368-Glu2627 (Uniprot#: Q99973)

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for TEP1 Antibody - BSA Free

TEP1 Antibody

Immunohistochemistry-Paraffin: TEP1 Antibody [NBP3-42356] -

Immunohistochemistry-Paraffin: TEP1 Antibody [NBP3-42356] - DAB staining on IHC-P; Samples: Human Kidney Tissue; Primary Ab: 10ug/ml NBP3-42356; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
TEP1 Antibody

Western Blot: TEP1 Antibody [NBP3-42356] -

Western Blot: TEP1 Antibody [NBP3-42356] - Sample: Recombinant protein.
TEP1 Antibody

Immunohistochemistry-Paraffin: TEP1 Antibody [NBP3-42356] -

Immunohistochemistry-Paraffin: TEP1 Antibody [NBP3-42356] - DAB staining on fromalin fixed paraffin-embedded stomach tissue

Applications for TEP1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

5-20ug/mL

Immunohistochemistry-Paraffin

5-20ug/mL

Western Blot

0.5-2ug/mL

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS, pH7.4, 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TEP1

Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes. Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TP1). Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death. High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression levels of TP1 do not correlate with malignancy. At least two isoforms of TP1 are known to exist.

Alternate Names

p240telomerase protein component 1, telomerase-associated protein 1VAULT2, TLP1p80 telomerase homolog, TP1Telomerase protein 1, TROVE domain family, member 1, TROVE1

Gene Symbol

TEP1

Additional TEP1 Products

Product Documents for TEP1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for TEP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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