TFEB Antibody (S05-0D7)

Name: TFEB Antibody (S05-0D7)
Brand: Novus Biologicals
SKU: NBP3-14901
Price: 479 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-14901

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S05-0D7 expressed in HEK293

View all TFEB Primary Antibodies »

Product Specifications

Immunogen

Recombinant protein of human TFEB (Uniprot#: P19484)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TFEB Antibody (S05-0D7)

Western Blot: TFEB Antibody (S05-0D7) [NBP3-14901]

Western Blot: TFEB Antibody (S05-0D7) [NBP3-14901] - Western blot detection of TFEB in A549, HL-60 cell lysates using TFEB Rabbit mAb (1:1000 diluted). Predicted band size: 53kDa. Observed band size: 65-70kDa.

Immunohistochemistry: TFEB Antibody (S05-0D7) [NBP3-14901]

Immunohistochemistry: TFEB Antibody (S05-0D7) [NBP3-14901] - Immunohistochemical of TFEB in Human lung cancer tissue using TFEB antibody at dilution 1/20

Applications for TFEB Antibody (S05-0D7)

Application

Recommended Usage

Immunohistochemistry

1/50

Western Blot

1/1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TFEB

Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta

Long Name

Transcription Factor EB

Alternate Names

ALPHATFEB, BHLHE35, TCFEB

Gene Symbol

TFEB

Additional TFEB Products

Product Documents for TFEB Antibody (S05-0D7)

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Certificate of Analysis

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Product Specific Notices for TFEB Antibody (S05-0D7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Autophagy

Basic Helix-Loop-Helix (bHLH) Transcription Factors

Lysosomal Enzymes

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