TH 257

Catalog # Availability Size / Price Qty
6899/5
6899/25
LIMK Inhibitors Small Molecule
1 Image
Description: Potent and selective allosteric LIMK 1/2 inhibitor

Chemical Name: N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide

Purity: ≥98%

Product Details
Reviews

Biological Activity

Potent and selective allosteric LIMK 1/2 inhibitor (IC50 values are 84 and 39 nM, respectively). Inhibits cofilin phosphorylation in vitro. Exhibits no significant activity against the wider kinome.

Technical Data

M.Wt:
422.54
Formula:
C24H26N2O3S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
2244678-29-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the TH 257 probe summary on the SGC website.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for TH 257

There are currently no reviews for this product. Be the first to review TH 257 and earn rewards!

Have you used TH 257?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.