Thromboxane synthase Antibody (OTI2C1)

Novus Biologicals | Catalog # NBP2-02710

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # OTI2C1
View all Thromboxane synthase Primary Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human TBXAS1(NP_001052) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

60.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Thromboxane synthase Antibody (OTI2C1)

Western Blot: Thromboxane synthase Antibody (2C1) [NBP2-02710] Analysis of extracts (35ug) from 9 different cell lines by using anti-Thromboxane synthase monoclonal antibody.
Immunocytochemistry/ Immunofluorescence: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Immunocytochemistry/ Immunofluorescence: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Immunocytochemistry/Immunofluorescence: Thromboxane synthase Antibody (2C1) [NBP2-02710] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY Thromboxane synthase.
Immunohistochemistry-Paraffin: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Immunohistochemistry-Paraffin: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Immunohistochemistry-Paraffin: Thromboxane synthase Antibody (2C1) [NBP2-02710] - Staining of paraffin-embedded Human liver tissue using anti-Thromboxane synthase mouse monoclonal antibody.
Flow Cytometry: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Flow Cytometry: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Flow Cytometry: Thromboxane synthase Antibody (2C1) [NBP2-02710] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-Thromboxane synthase antibody, and then analyzed by flow cytometry.
Western Blot: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Western Blot: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Western Blot: Thromboxane synthase Antibody (2C1) [NBP2-02710] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Thromboxane synthase (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Thromboxane synthase.
Immunohistochemistry-Paraffin: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Immunohistochemistry-Paraffin: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Immunohistochemistry-Paraffin: Thromboxane synthase Antibody (2C1) [NBP2-02710] - Staining of paraffin-embedded Human Kidney tissue using anti-Thromboxane synthase mouse monoclonal antibody.
Flow Cytometry: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Flow Cytometry: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Flow Cytometry: Thromboxane synthase Antibody (2C1) [NBP2-02710] - Analysis of Hela cells, using anti-Thromboxane synthase antibody, (Red), compared to a nonspecific negative control antibody (Blue).
Flow Cytometry: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Flow Cytometry: Thromboxane synthase Antibody (OTI2C1) [NBP2-02710]

Flow Cytometry: Thromboxane synthase Antibody (2C1) [NBP2-02710] - Analysis of Jurkat cells, using anti-Thromboxane synthase antibody, (Red), compared to a nonspecific negative control antibody (Blue).

Applications for Thromboxane synthase Antibody (OTI2C1)

Application
Recommended Usage

Flow Cytometry

1:100

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:50

Immunohistochemistry-Paraffin

1:50

Western Blot

1:1000-2000

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Advanced Features

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

0.86 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Thromboxane synthase

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Alternate Names

CYP5A1family 5, subfamily A, polypeptide 1, CYP5FLJ52771, EC 5.3.99.5, GHOSAL, platelet, cytochrome P450, subfamily V, thromboxane A synthase 1 (platelet), thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A), thromboxane A synthase 1 (platelet, cytochrome P450, subfamily V), thromboxane-A synthase, TXA synthase

Entrez Gene IDs

6916 (Human)

Gene Symbol

TBXAS1

Additional Thromboxane synthase Products

Product Documents for Thromboxane synthase Antibody (OTI2C1)

Certificate of Analysis

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Product Specific Notices for Thromboxane synthase Antibody (OTI2C1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Thromboxane synthase Antibody (OTI2C1)

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Protocols

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