TMEFF2/Tomoregulin-2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-84362

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (99%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all TMEFF2/Tomoregulin-2 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TMEFF2/Tomoregulin-2 Antibody - BSA Free

Western Blot: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Western Blot: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Western Blot: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362] - Analysis in human cell line U-87 MG.
Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362] - Staining of human prostate shows weak granular cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362] - Staining of human Cerebellum shows moderate granular cytoplasmic positivity in Purkinje cells.
Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362] - Staining of human Cerebral cortex shows moderate granular cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362]

Immunohistochemistry-Paraffin: TMEFF2/Tomoregulin-2 Antibody [NBP1-84362] - Staining of human Skeletal muscle shows no positivity in myocytes as expected.

Applications for TMEFF2/Tomoregulin-2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMEFF2/Tomoregulin-2

TMEFF2(transmembrane protein with EGF-like and two follistatin-like domains 2), a gene encoding a plasma membrane protein with two follistatin-like domains and one epidermal growth factor-like domain, had limited normal tissue distribution and was highly overexpressed in prostate cancer. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. Down-regulated in tumor cell lines in response to a high level of methylation in the 5' region. Clone J4B6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TMEFF2 protein.

Long Name

Transmembrane Protein with EFG-like and two Follistatin-like Domains

Alternate Names

TENB2, Tomoregulin-2, Tomoregulin2

Gene Symbol

TMEFF2

Additional TMEFF2/Tomoregulin-2 Products

Product Documents for TMEFF2/Tomoregulin-2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for TMEFF2/Tomoregulin-2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Biomarkers
EGF Family

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Protocols

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FAQs

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