TNF RI/TNFRSF1A Antibody (001) [HRP]

Name: TNF RI/TNFRSF1A Antibody (001) [HRP]
Brand: Novus Biologicals
SKU: NBP2-89687H
Price: 559 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-89687H

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

HRP

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 001 expressed in HEK293

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Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human TNF RI/TNFRSF1A (Accession#: NP_001056.1; Met1-Thr211).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for TNF RI/TNFRSF1A Antibody (001) [HRP]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TNF RI/TNFRSF1A

The protein encoded by the TNF Receptor I gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. (provided by RefSeq)

Long Name

Tumor Necrosis Factor Receptor I

Alternate Names

CD120a, TNFRI, TNFRSF1A

Gene Symbol

TNFRSF1A

Additional TNF RI/TNFRSF1A Products

Product Documents for TNF RI/TNFRSF1A Antibody (001) [HRP]

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Certificate of Analysis

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Product Specific Notices for TNF RI/TNFRSF1A Antibody (001) [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.