Tocriscreen Kinase Inhibitor Toolbox I
Biological Activity
A collection of 80 kinase inhibitors supplied pre-dissolved in DMSO (250 μL 10 mM solution). Comprises a subset of the Tocriscreen Plus (Cat. No. 5840) compound library. Contains compounds covering more than 40 different target kinases including VEGFR, AKT, CDKs, EGFR, p38 MAPK, Src Kinases and TGF-β receptors.This replaces Tocriscreen Kinase Inhibitor Toolbox (Cat. No. 3514).
Key Format and Product Details
- 96-well rack with Matrix storage tubes & SepraSeal caps
- Pre-dissolved in DMSO
- Many compounds are exclusive to Tocris
- Full chemical and biological data available
- Exceptional purity
Request Compound List
A list of the compounds available in the Tocriscreen Kinase Inhibitor Toolbox I can be requested in Excel or SD format via our Tocriscreen & Custom Library Inquiries form.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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GSK3 is a negative regulator of the thermogenic program in brown adipocytes.
Markussen
Sci Rep, 2018;8:3469 -
A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.
Azad et al.
Nat.Commun., 2018;9
Product Datasheets
Reconstitution Calculator
Citations for Tocriscreen Kinase Inhibitor Toolbox I
The citations listed below are publications that use Tocris products. Selected citations for Tocriscreen Kinase Inhibitor Toolbox I include:
4 Citations: Showing 1 - 4
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GSK3 is a negative regulator of the thermogenic program in brown adipocytes.
Authors: Markussen Et al.
Sci.Rep. 2018;8:3469
-
GSK3 is a negative regulator of the thermogenic program in brown adipocytes.
Authors: Markussen Et al.
Sci.Rep. 2018;8:3469
-
p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy.
Authors: Sandilands Et al.
Cell Signal. 2015;27:1816
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SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest.
Authors: Tandon Et al.
PLoS One 2015;10:e0119346
FAQs
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