Tocriscreen Library of FDA-Approved Compounds: R&D Systems
Catalog Number: 5932
Biological Activity
A library of 160 FDA-approved compounds. Comprises a subset of the Tocriscreen Plus (Cat. No. 5840) compound library. Contains compounds covering a range of therapeutic classes e.g. the cardiovascular and nervous systems and research areas such as cancer and immunology. Includes both established gold-standard compounds, e.g. tamoxifen, paclitaxel, as well as more recent highly selective, targeted compounds, such as gefitinib and axitinib.
Key Format and Product Details
  • All compounds are FDA-approved
  • Full chemical and biological data available
  • 96-well racks with Matrix storage tubes & SepraSeal caps
  • Compounds arranged 80 per rack with 2 racks per library
  • Pre-dissolved in 250 μL 10 mM DMSO solutions
  • Compounds produced to same high chemical standard as Tocris catalog
Technical Data
  • Storage:
    Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
The Compound list for this product may be requested from www.tocris.com/screening
Background References
  1. Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules.
    Li et al.
    Cell Research, 2011;21:196
  2. Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.
    Hattori et al.
    Proc.Natl.Acad.Sci.USA, 2010;107:3546
  3. Small Molecules Enhance CRISPR Genome Editing in Pluripotent Stem Cells.
    Yu et al.
    Cell Stem Cell, 2015;16:142
  4. The University of New Mexico Center for Molecular Discovery.
    Edwards et al.
    Comb.Chem.High Throughput Screen., 2014;17:256
  5. Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons.
    Li et al.
    Cell Stem Cell, 2015;17:195
  6. Cell-based potassium ion channel screening using the FluxORTM assay.
    Beacham et al.
    J.Biomol.Screen., 2010;15:44
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

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