TOPORS Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-39060

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: IVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFARSPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDETPGPSYSSSEQVHVTMSSLL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TOPORS Antibody - BSA Free

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060]

Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060] - Staining in human testis and pancreas tissues using anti-TOPORS antibody. Corresponding TOPORS RNA-seq data are presented for the same tissues.

Applications for TOPORS Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TOPORS

TOPORS functions as an ubiquitin-protein E3 ligase and as an E3 SUMO1-protein ligase. Can both ubiquitinate and sumoylate p53

Alternate Names

EC 6.3.2.-, LUNtopoisomerase I binding, arginine/serine-rich, p53-binding protein 3, P53BP3, retinitis pigmentosa 31 (autosomal dominant), RP31, SUMO1-protein E3 ligase Topors, topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase, Topoisomerase I-binding arginine/serine-rich protein, Topoisomerase I-binding RING finger protein, TP53BPLE3 ubiquitin-protein ligase Topors, Tumor suppressor p53-binding protein 3

Gene Symbol

TOPORS

UniProt

Additional TOPORS Products

Product Documents for TOPORS Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TOPORS Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

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