TRAF-6 Antibody - BSA Free

Name: TRAF-6 Antibody - BSA Free
Brand: Novus Biologicals
SKU: NBP1-80825
Price: 429 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-80825

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Citations (2)

Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Bovine

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

View all TRAF-6 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPV

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (84%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit TRAF-6 Antibody - BSA Free (NBP1-80825) is a polyclonal antibody validated for use in IHC and ICC/IF. Anti-TRAF-6 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for TRAF-6 Antibody - BSA Free

Immunohistochemistry-Paraffin: TRAF-6 Antibody [NBP1-80825]

Immunohistochemistry-Paraffin: TRAF-6 Antibody [NBP1-80825] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Immunohistochemistry: TRAF-6 Antibody [NBP1-80825]

Immunohistochemistry: TRAF-6 Antibody [NBP1-80825] - Staining of human rectum shows moderate cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: TRAF-6 Antibody [NBP1-80825]

Immunohistochemistry-Paraffin: TRAF-6 Antibody [NBP1-80825] - Staining of human testis shows moderate cytoplasmic/ membranous positivity in cells in seminiferous ducts.

Immunohistochemistry-Paraffin: TRAF-6 Antibody [NBP1-80825]

Immunohistochemistry-Paraffin: TRAF-6 Antibody [NBP1-80825] - Staining of human endometrium shows moderate cytoplasmic/ membranous positivity in glandular cells.

Immunohistochemistry-Paraffin: TRAF-6 Antibody [NBP1-80825]

Immunohistochemistry-Paraffin: TRAF-6 Antibody [NBP1-80825] - Staining of human colon shows strong cytoplasmic positivity in lymphoid cells.

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Applications for TRAF-6 Antibody - BSA Free

Application

Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200-1:500

Application Notes

For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAF-6

The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.

Long Name

TNF Receptor-Associated Factor 6

Alternate Names

TRAF6

Entrez Gene IDs

7189 (Human)

Gene Symbol

TRAF6

Additional TRAF-6 Products

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Product Specific Notices for TRAF-6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.