TRIB3 Antibody

Novus Biologicals | Catalog # NB100-56398

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot, Immunocytochemistry/ Immunofluorescence

Cited:

Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all TRIB3 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to amino acid residues 315-332 of human TRIB3. Genbank accession number: NM_021158.

Specificity

This detects a protein of approximate mol. wt. of 40 kDa in human liver lysate.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRIB3 Antibody

Western Blot: TRIB3 Antibody [NB100-56398]

Western Blot: TRIB3 Antibody [NB100-56398]

Western Blot: TRIB3 Antibody [NB100-56398] - Analysis of TRIB3 in human liver lysate.

Applications for TRIB3 Antibody

Application
Recommended Usage

Western Blot

1-3 ug/ml
Application Notes
)

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRIB3

A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.

Alternate Names

C20orf97, dJ1103G7.3, neuronal cell death inducible putative kinase, Neuronal cell death-inducible putative kinase, NIPK, p65-interacting inhibitor of NF-kappaB, p65-interacting inhibitor of NF-kappa-B, SINK, SKIP3, TRB-3, TRB3chromosome 20 open reading frame 97, tribbles homolog 3, tribbles homolog 3 (Drosophila)

Entrez Gene IDs

57761 (Human)

Gene Symbol

TRIB3

UniProt

Q96RU7 (Human)

Additional TRIB3 Products

Product Documents for TRIB3 Antibody

Certificate of Analysis

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Product Specific Notices for TRIB3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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