TrkB Antibody - Azide Free

Novus Biologicals | Catalog # NBP2-29660

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide Free
View all TrkB Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. Accession # Q63604

Specificity

Specific for the ~93 kDa TrkB protein in Western blots.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

93 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit TrkB Antibody - Azide Free (NBP2-29660) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for TrkB Antibody - Azide Free

Western Blot: TrkB Antibody [NBP2-29660]

Western Blot: TrkB Antibody [NBP2-29660]

Western Blot: TrkB Antibody [NBP2-29660] - rat synaptic membrane preparation showing specific immunolabeling of the ~ 93k TrkB protein.

Applications for TrkB Antibody - Azide Free

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol

Format

Azide Free

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TrkB

Tropomyosin-receptor-kinase (TRK) receptors are members of the receptor tyrosine kinase family and include TrkA, TrkB and TrkC. Each of these receptor types has different binding affinities to the neurotrophins nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT-3). TrkB has the highest affinity to binding BDNF which plays critical roles in the function and survival of neurons in the CNS (Soppet et al., 1991; Klein et al., 1991). Additionally, alterations in expression of TrkB have been associated with Alzheimer's disease (Ferrer et al., 1999; Chen et al., 2008).

Long Name

Neurotrophic Tyrosine Kinase Receptor B

Alternate Names

NTRK2

Entrez Gene IDs

25054 (Rat)

Gene Symbol

NTRK2

UniProt

Q63604 (Rat)

Additional TrkB Products

Product Documents for TrkB Antibody - Azide Free

Certificate of Analysis

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Product Specific Notices for TrkB Antibody - Azide Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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