293 results for "TrkB" in Products
TrkB Products
Members of the Trk family (TrkA, B, and C) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth.
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, B/N, Simple Western |
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | Q16620.1 |
| Applications: | Bioactivity |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #75133 |
| Applications: | IHC, WB |
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
| Reactivity: | Human |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: TrkB [p Tyr816] Antibody [NBP1-03499]](https://resources.rndsystems.com/images/products/TrkB-[p-Tyr816]-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-03499-img0001.jpg "Immunocytochemistry/ Immunofluorescence: TrkB [p Tyr816] Antibody [NBP1-03499]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #72509 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, Simple Western, CyTOF-ready |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SC0556 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Mouse |
| Source: | NS0 |
| Accession #: | P15209 |
| Applications: | Bioactivity |
Potent TrkB agonist
| Chemical Name: | N,N',N''Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2E1 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: TrkB Antibody (OTI2E1) [NBP1-47898]](https://resources.rndsystems.com/images/products/TrkB-Antibody-2E1-Western-Blot-NBP1-47898-img0007.jpg "Western Blot: TrkB Antibody (OTI2E1) [NBP1-47898]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rat IgG2B Monoclonal Clone #225105 |
| Applications: | IHC, WB |
His-tag
| Reactivity: | Mouse |
| Source: | NS0 |
| Accession #: | P15209 |
| Applications: | Bioactivity |
| Reactivity: | Human |
| Assay Range: | 93.8-6000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #10B6C4 |
| Applications: | IHC, WB, ELISA |
![Western Blot: TrkB Antibody (10B6C4)BSA Free [NBP2-52524]](https://resources.rndsystems.com/images/products/TrkB-Antibody-10B6C4-Western-Blot-NBP2-52524-img0007.jpg "Western Blot: TrkB Antibody (10B6C4)BSA Free [NBP2-52524]")
Analyzed by SEC-MALS
| Reactivity: | Human |
| Source: | CHO |
| Accession #: | Q16620.1 |
| Applications: | Bioactivity |
TrkB receptor antagonist
| Chemical Name: | N-[2-[[(Hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]benzo[b]thiophene-2-carboxamide |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2E1 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: TrkB Antibody (OTI2E1)Azide and BSA Free [NBP2-74624]](https://resources.rndsystems.com/images/products/TrkB-Antibody-OTI2E1-Azide-and-BSA-Free-Western-Blot-NBP2-74624-img0001.jpg "Western Blot: TrkB Antibody (OTI2E1)Azide and BSA Free [NBP2-74624]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #72509 |
| Applications: | Flow |
TrkB agonist
| Alternate Names: | 7,8-DHF |
| Chemical Name: | 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one |
| Purity: | ≥98% |
Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC
| Chemical Name: | N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea |
| Purity: | ≥98% |
TrkB receptor antagonist
| Purity: | ≥95% |
TrkB and TrkC agonist; brain penetrant
| Chemical Name: | 2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol |
| Purity: | ≥97% |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #8D2E8 |
| Applications: | WB, ELISA, CyTOF-ready |
![Western Blot: TrkB Antibody (8D2E8)BSA Free [NBP2-52523]](https://resources.rndsystems.com/images/products/TrkB-Antibody-8D2E8-Western-Blot-NBP2-52523-img0004.jpg "Western Blot: TrkB Antibody (8D2E8)BSA Free [NBP2-52523]")