TWS 119

Catalog # Availability Size / Price Qty
3835/10
TWS 119 | CAS No. 1507095-58-0 | GSK-3 Inhibitors
1 Image
Description: GSK-3β inhibitor; induces neuronal differentiation in ESCs

Chemical Name: 3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxyphenol ditrifluoroacetate

Product Details
Reviews

Biological Activity

Inhibitor of glycogen synthase kinase-3β (IC50 = 30 nM). Induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESCs).

Technical Data

Formula:
C18H14N4O2.2CF3CO2H
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage:
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
CAS No:
1507095-58-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Synthetic small molecules that control stem cell fate.
    Ding et al.
    Proc.Natl.Acad.Sci., 2003;100:7632
  2. Canonical wnt signaling maintains the quiescent stage of hepatic stellate cells.
    Kordes et al.
    Biochem.Biophys.Res.Comm., 2008;367:116

Product Datasheets

or select another batch:
Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for TWS 119

There are currently no reviews for this product. Be the first to review TWS 119 and earn rewards!

Have you used TWS 119?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.