Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Simple Western

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 972106

Format

Azide and BSA Free
View all UCH-L1/PGP9.5 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human UCH-L1/PGP9.5

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Description

Human UCH-L1/PGP9.5 MAb (Clone 972106)

Scientific Data Images for UCH-L1/PGP9.5 Antibody (972106) - Azide and BSA Free

Immunohistochemistry-Paraffin: UCH-L1/PGP9.5 Antibody (972106) - Azide and BSA Free [MAB60071]

Immunohistochemistry-Paraffin: UCH-L1/PGP9.5 Antibody (972106) - Azide and BSA Free [MAB60071]

Immunohistochemistry-Paraffin: UCH-L1 Antibody (972106) [MAB60071] - Antibody was detected in immersion fixed paraffin-embedded sections of human brain caudate nucleus tissue.
Simple Western: UCH-L1/PGP9.5 Antibody (972106)Azide and BSA Free [MAB60071]

Simple Western: UCH-L1/PGP9.5 Antibody (972106)Azide and BSA Free [MAB60071]

Simple Western: UCH-L1/PGP9.5 Antibody (972106) [MAB60071] - PC-12 cell lysate. Antibody at 5 ug/mL.

Applications for UCH-L1/PGP9.5 Antibody (972106) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Simple Western

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

0.62 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: UCH-L1/PGP9.5

Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCHL1) is a soluble cytoplasmic protein found in neurons and in cells of the diffuse neuroendocrine system, and their respective tumors. Therefore, UCH-L1 has been widely used as a peripheral nerve fiber marker. UCHL-1 functions as a tissue-specific ubiquitin carboxyl terminal hydrolase isoenzyme involved in the processing of both ubiquitin precursors and ubiquitinated proteins.

UCH L1 is down-regulated in brains from Parkinson disease and Alzheimer disease patients, and certian site specific mutations in the UCHL1 gene can either increase or decrese the risk of Parkinson's and/or Alzheimer's neurodegenerative diseases.

Human UCHL 1 and the closely related UCHL3 protein have one of the most complicated knot structures ever discovered, with five knot crossings. This knot structure is expected to help the protein resist degradation in the proteasome.

Long Name

Ubiquitin C-terminal Hydrolase L1

Alternate Names

PARK5, PGP9.5, UCHL1

Gene Symbol

UCHL1

Additional UCH-L1/PGP9.5 Products

Product Documents for UCH-L1/PGP9.5 Antibody (972106) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for UCH-L1/PGP9.5 Antibody (972106) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for UCH-L1/PGP9.5 Antibody (972106) - Azide and BSA Free

There are currently no reviews for this product. Be the first to review UCH-L1/PGP9.5 Antibody (972106) - Azide and BSA Free and earn rewards!

Have you used UCH-L1/PGP9.5 Antibody (972106) - Azide and BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies