URB 602

Key Product Details

Product Description

URB 602 is a non-competitive MAGL inhibitor. Exhibits selectivity for MAGL over FAAH, diacylglycerol lipase and COX2. Blocks 2-AG hydrolysis in rat brain slices. Enhances stress-induced analgesia in rats.

Product Specifications for URB 602

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for URB 602

The following data is based on the product molecular weight 295.38.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.39 mL	16.93 mL	33.85 mL
5 mM	0.68 mL	3.39 mL	6.77 mL
10 mM	0.34 mL	1.69 mL	3.39 mL
50 mM	0.07 mL	0.34 mL	0.68 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Makara Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus. Nat.Neurosci. 2005 PMID: 16116451
• Hohmann An endocannabinoid mechanism for stress-induced analgesia. Nature. 2005 PMID: 15973410

Product Documents for URB 602