Catalog Number: 6020
Chemical Name: N-[1,1'-Biphenyl]-3-yl-carbamic acid cyclohexyl ester
Biological Activity
Non-competitive MAGL inhibitor. Exhibits selectivity for MAGL over FAAH, diacylglycerol lipase and COX2. Blocks 2-AG hydrolysis in rat brain slices. Enhances stress-induced analgesia in rats.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
  • Storage:
    Store at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. An endocannabinoid mechanism for stress-induced analgesia.
    Hohmann et al.
    Nature, 2005;435:1108
  2. Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus.
    Makara et al.
    Nat.Neurosci., 2005;8:1139
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