URB 602
Discontinued Product
Chemical Name: N-[1,1'-Biphenyl]-3-yl-carbamic acid cyclohexyl ester
Purity: ≥99%
Biological Activity
URB 602 is a non-competitive MAGL inhibitor. Exhibits selectivity for MAGL over FAAH, diacylglycerol lipase and COX2. Blocks 2-AG hydrolysis in rat brain slices. Enhances stress-induced analgesia in rats.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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An endocannabinoid mechanism for stress-induced analgesia.
Hohmann et al.
Nature, 2005;435:1108 -
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus.
Makara et al.
Nat.Neurosci., 2005;8:1139
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