VEGFR1/Flt-1 Antibody (CL0344) - Azide and BSA Free

Name: VEGFR1/Flt-1 Antibody (CL0344) - Azide and BSA Free
Brand: Novus Biologicals
SKU: NBP3-43979
Price: 539 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-43979

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ Clone # CL0344

Format

Azide and BSA Free

View all VEGFR1/Flt-1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was generated using a recombinant protein sequence of P17948, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Scientific Data Images for VEGFR1/Flt-1 Antibody (CL0344) - Azide and BSA Free

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NBP3-43979]

Analysis in human placenta and tonsil tissues using NBP3-43979 antibody. Corresponding VEGFR1/Flt-1 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NBP3-43979]

Staining of human kidney shows strong cytoplasmic positivity in endothelial cells.

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NBP3-43979]

Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NBP3-43979]

Staining of human small intestine shows strong cytoplasmic positivity in endothelial cells, as well as positivity in smooth muscle.

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NBP3-43979]

Staining of human tonsil shows no cytoplasmic positivity in lymphoid cells as expected.

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Applications for VEGFR1/Flt-1 Antibody (CL0344) - Azide and BSA Free

Application

Recommended Usage

Immunohistochemistry-Paraffin

1:200 - 1:500

Application Notes

For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: VEGFR1/Flt-1

Receptors for VEGF, VEGFB and PGF have tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. VEGF and its high-affinity binding receptors--the tyrosine kinases FLK1 and FLT1--are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis.

Long Name

Vascular Endothelial Growth Factor Receptor 1

Alternate Names

Flt-1, FLT1, FRT, VEGF R1, VEGFR-1

Gene Symbol

FLT1

Additional VEGFR1/Flt-1 Products

Product Documents for VEGFR1/Flt-1 Antibody (CL0344) - Azide and BSA Free

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Certificate of Analysis

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Product Specific Notices for VEGFR1/Flt-1 Antibody (CL0344) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.