Vincristine sulfate

Tocris Bioscience | Catalog # 1257

Disrupts microtubules
Tocris Bioscience

Key Product Details

Description

Disrupts microtubules
View all Microtubule Binding Compounds »

Product Description

Vincristine sulfate is a anticancer agent; microtubule disrupter. Induces apoptosis in human lymphoma cells.

Product Specifications for Vincristine sulfate

Molecular Weight

923.04

Formula

C46H56N4O10.H2SO4

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

22-Oxovincaleukoblastine

CAS Number

2068-78-2

PubChem ID

249332

InChI Key

AQTQHPDCURKLKT-JKDPCDLQSA-N

SMILES

OS(O)(=O)=O.[H][C@@]23N(C=O)C1=CC(OC)=[C@]([C@@]7([C@](OC)=O)C[C@H]6C[C@@](O)(CC)CN(CCC8=C7NC9=C8C=CC=C9)C6)C=C1[C@@]52[C@](N(CC5)CC=C4)([H])[C@]4(CC)[C@@H](OC(C)=O)[C@]([C@](OC)=O)3O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100

Preparing Stock Solutions for Vincristine sulfate

The following data is based on the product molecular weight 923.04.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.08 mL 5.42 mL 10.83 mL
5 mM 0.22 mL 1.08 mL 2.17 mL
10 mM 0.11 mL 0.54 mL 1.08 mL
50 mM 0.02 mL 0.11 mL 0.22 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 23 publications citing the usage of this product.

Product Documents for Vincristine sulfate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Vincristine sulfate

For research use only

⚠ WARNING: This product can expose you to chemicals including Vincristine sulfate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Related Research Areas

Microtubules

Citations for Vincristine sulfate

Customer Reviews for Vincristine sulfate (1)

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  • Paclitaxel, docetaxel, vincristine, vinblastine, colchicine, cisplatin, and mitoxantrone screen for Human epidermal carcinoma
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Human epidermal carcinoma cell line
    Verified Customer | Posted 11/17/2019
    Human epidermal carcinoma cell line was treated with Paclitaxel, docetaxel, vincristine, vinblastine, colchicine, cisplatin, and mitoxantrone which purchased from Tocris Bioscience.
    Vincristine sulfate 1257

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