Selective blocker of P-type calcium channels (IC
< 1 - 3 nM). Also inhibits N-type channels at micromolar concentrations.
217H 360N 68O 60S 10
(Modifications: Disulfide bridge between 4 - 20, 12 - 25, 19 - 36, 27 - 34)
Soluble in water
Desiccate at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Calcium channels coupled to glutamate release identified by ω-Aga-IVA.
Turner et al.
Protease treatment of cerebellar purkinje cells renders ω-agatoxin IVA-sensitive Ca 2+ channels insensitive to inhibition by ω-conotoxin GVIA.
Tringham et al.
Splicing of α 1A subunit gene generates phenotypic variants of P- and Q-type calcium channels.
Bourinet et al.
P-type calcium channels blocked by the spider toxin ω-Aga-IVA.
Mintz et al.
The citations listed below are publications that use Tocris products. Selected citations for ω-Agatoxin IVA include:
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