Biological ActivitySelective blocker of CaV2.1 P/Q-type calcium channels.
(Modifications: Disulfide bridge between 4 - 20, 12 - 25, 19 - 36, 27 - 34)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
A novel type of calcium channel sensitive to ω-agatoxin-TK in cultured rat cerebral cortical neurons.
Teramoto et al.
Brain Res., 1997;756:225
High-affinity inhibition of glutamate release from corticostriatal synapses by ω-agatoxin TK.
Barral et al.
A novel peptide from funnel web spider venom, ω-Aga-TK, selectively blocks P-type calcium channels.
Teramoto et al.
Citations for ω-Agatoxin TK
The citations listed below are publications that use Tocris products. Selected citations for ω-Agatoxin TK include:
5 Citations: Showing 1 - 5
Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.
Authors: Cramer Et al.
Purkinje cell dysfunction and delayed death in plasma membrane calcium ATPase 2-heterozygous mice.
Authors: Fakira Et al.
J Neurosci 2012;51:22
Concurrent imaging of synaptic vesicle recycling and calcium dynamics.
Authors: Li Et al.
Front Mol Neurosci 2011;4:34
Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability.
Authors: Grubb and Burrone
Mol Cell Neurosci 2010;465:1070
Sustained glutamate receptor activation down-regulates GABAB receptors by shifting the balance from recycling to lysosomal degradation.
Authors: Maier Et al.
J Biol Chem 2010;285:35606
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