Catalog Number: 1084
Biological Activity
Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.
Technical Data
  • M.Wt:
    2749
  • Formula:
    C106H178N40O32S7
  • Sequence:
    CKGKGAPCRKTMYDCCSGSCGRRGKC

    (Modifications: Disulfide bridge between 1 - 16, 8 - 20, 15 - 26, Cys-26 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    147794-23-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license from the University of Utah.
Background References
  1. A new conus peptide ligand for mammalian presynaptic Ca2+ channels.
    Hillyard et al.
    Neuron, 1992;9:69
  2. Inhibition of Ca2+ channels in rat central and peripheral neurons by ω-conotoxin MVIIC.
    McDonough et al.
    J.Neurosci., 1996;16:2612
Citations:

The citations listed below are publications that use Tocris products. Selected citations for ω-Conotoxin MVIIC include:

3 Citations: Showing 1 - 3
Filter your results:

  1. Swelling-activated Ca2+ channels trigger Ca2+ signals in Merkel cells.
    Authors: Haeberle Et al.
    Nat Commun ;3:e1750
  2. σ-1 receptor antagonism restores injury-induced decrease of voltage-gated Ca2+ current in sensory neurons.
    Authors: Pan Et al.
    PLoS One 2014;350:290
  3. Sustained glutamate receptor activation down-regulates GABAB receptors by shifting the balance from recycling to lysosomal degradation.
    Authors: Maier Et al.
    J Biol Chem 2010;285:35606

Have you used ω-Conotoxin MVIIC?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information