Catalog Number: 1084
Biological Activity
Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Disulfide bridge between 1 - 16, 8 - 20, 15 - 26, Cys-26 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license from the University of Utah.
Background References
  1. A new conus peptide ligand for mammalian presynaptic Ca2+ channels.
    Hillyard et al.
    Neuron, 1992;9:69
  2. Inhibition of Ca2+ channels in rat central and peripheral neurons by ω-conotoxin MVIIC.
    McDonough et al.
    J.Neurosci., 1996;16:2612

The citations listed below are publications that use Tocris products. Selected citations for ω-Conotoxin MVIIC include:

Showing Results 1 - 3 of 3

  1. σ-1 receptor antagonism restores injury-induced decrease of voltage-gated Ca2+ current in sensory neurons.
    Authors: Pan Et al.
    PLoS One
  2. Sustained glutamate receptor activation down-regulates GABAB receptors by shifting the balance from recycling to lysosomal degradation.
    Authors: Maier Et al.
    J Biol Chem
  3. Swelling-activated Ca2+ channels trigger Ca2+ signals in Merkel cells.
    Authors: Haeberle Et al.
    Nat Commun
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