Chemical Name: (3S,11E)-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione
Biological ActivityZearalenone is a mycotoxin produced by several species of Fusarium fungi. Binds to the estrogen receptor (ER) (IC50 values are 166 and 240 nM for ERβ and ERα respectively) and stimulates the transcriptional activity of both subtypes at concentrations between 1 - 10 nM. Also stimulates growth of T47D breast cancer cells.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β.
Kuiper et al.
Characterization of the estrogenic activities of zearalenone and zeranol in vivo and in vitro.
Takemura et al.
J.Steroid Biochem.Molec.Biol., 2007;103:170
Effects of zearalenone and α-Zearalenol in comparison with ralox. on T47D cells.
Khosrokhavar et al.
Citation for Zearalenone
The citations listed below are publications that use Tocris products. Selected citations for Zearalenone include:
1 Citation: Showing 1 - 1
Hydrophobized Reversed-Phase Adsorbent for Protection of Dairy Cattle against Lipophilic Toxins from Diet. Efficiensy in Vitro and in Vivo.
Authors: Sotnichenko Et al.
Toxins (Basel) 2019;11
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Zearalenone
There are currently no reviews for this product. Be the first to review Zearalenone and earn rewards!
Have you used Zearalenone?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image