Zeta Opioid Receptor Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-30451

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

Between 627 and 677

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Zeta Opioid Receptor Antibody - BSA Free

Zeta Opioid Receptor Antibody

Immunohistochemistry;Zeta Opioid Receptor Antibody[NBP3-30428]

Immunohistochemistry;Zeta Opioid Receptor Antibody[NBP3-30428]Detection of human OGFR by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-OGFR used at a dilution of 1:1,000. Detection: DAB
Zeta Opioid Receptor Antibody

Immunoprecipitation:Zeta Opioid Receptor AntibodyNBP3-30451] -

Immunoprecipitation:Zeta Opioid Receptor AntibodyNBP3-30451] -Detection of human OGFR by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-OGFR antibody NBP3-30451 (lot NBP3-30451-1) used for IP at 6 µg per reaction. OGFR was also immunoprecipitated by rabbit anti-OGFR antibody. For blotting immunoprecipitated OGFR, NBP3-30451 was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Applications for Zeta Opioid Receptor Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Zeta Opioid Receptor

Zeta Opioid Receptor is the receptor for opioid growth factor (OGF), also known as Met-enkephalin. Met-enkephalin (met-Enk) is an opioid peptide that acts via three main subtypes of receptors referred to as mu, delta and zeta receptors. The first two receptor subtypes mediate the classic opioid effects of met-Enk, wheras zeta-receptors are reported to be involved in the non-opioid actions of the peptide. OGF (Met-enkephalin)is an inhibitory peptide that modulates cell proliferation and tissue organization during development, cellular renewal, cancer, wound healing, and angiogenesis. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. It has been found that the progression of some tumours is associated with the down regulation of opioid growth factor receptor expression.

Alternate Names

7-60, 7-60 protein, OGFr, opioid growth factor receptor, Protein 7-60, Zeta-type opioid receptor

Gene Symbol

OGFR

Additional Zeta Opioid Receptor Products

Product Documents for Zeta Opioid Receptor Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Zeta Opioid Receptor Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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