Catalog Number: 0746
Chemical Name: 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid, zinc complex
Biological Activity
Inhibitor of heme oxygenase, which generates the putative neurotransmitter CO.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in DMSO
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase.
    Brune and Ullrich
    Mol.Pharmacol., 1987;32:497
  2. Pitfalls using metalloporphyrins in carbon monoxide research.
    Grundemar and Ny
    TiPS, 1997;18:193
  3. Metalloporphyrins inhibit nitric oxide-dependent cGMP formation in vivo.
    Luo and Vincen
    Eur.J.Pharmacol., 1994;267:263
  4. Carbon monoxide a putative neural messenger.
    Verma et al.
    Science, 1993;259:381

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