Zinc protoporphyrin IX
Chemical Name: 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid, zinc complex
Biological Activity
Inhibitor of heme oxygenase, which generates the putative neurotransmitter CO.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase.
Brune and Ullrich
Mol.Pharmacol., 1987;32:497 -
Pitfalls using metalloporphyrins in carbon monoxide research.
Grundemar and Ny
TiPS, 1997;18:193 -
Metalloporphyrins inhibit nitric oxide-dependent cGMP formation in vivo.
Luo and Vincen
Eur.J.Pharmacol., 1994;267:263 -
Carbon monoxide a putative neural messenger.
Verma et al.
Science, 1993;259:381
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Citation for Zinc protoporphyrin IX
The citations listed below are publications that use Tocris products. Selected citations for Zinc protoporphyrin IX include:
1 Citation: Showing 1 - 1
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Data on characterization of metalloporphyrin-mediated HO-1 and DAF induction in rat glomeruli and podocytes.
Authors: Duann Et al.
Data Brief 2019;22:279
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