Catalog Number: 1051
Alternate Names: MJ 9184
Chemical Name: N-[5-[2-[(1,1-Dimethyl-2-phenylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulphonamide hydrochloride
Biological Activity
Potent and selective β2-adrenoceptor agonist (pKB values are 8.3 and < 5.7 for β 2 and β1 receptors respectively, as measured in human artery).
Technical Data
  • M.Wt:
    414.95
  • Formula:
    C19H26N2O4S
  • Solubility:
    Soluble to 5 mM in water and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    37000-20-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Beta-2 adrenergic activation of L-type Ca2+ current in cardiac myocytes.
    Arvydas Skeberdis et al.
    J.Pharmacol.Exp.Ther., 1997;283:452
  2. Agonist effects of zinterol at the mouse and human β3-adrenoceptor.
    Hutchinson et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 2006;373:158
  3. Four β-adrenoceptor subtypes in the mammalian heart.
    Kauman
    TiPS, 1997;18:70
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Zinterol hydrochloride include:

2 Citations: Showing 1 - 2
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  1. Caveolae compartmentalise β2-adrenoceptor signals by curtailing cAMP production and maintaining phosphatase activity in the sarcoplasmic reticulum of the adult ventricular myocyte.
    Authors: Macdougall Et al.
    J Mol Cell Cardiol 2012;52:388
  2. A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice.
    Authors: Eckle Et al.
    J Am Coll Cardiol 2008;118:3301

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