6 results for "5-HT1A Receptor Antagonists Small Molecules and Peptides" in Products
5-HT1A Receptor Antagonists Small Molecules and Peptides
The serotonin 5-HT1A receptor was the first 5-HT receptor to be fully sequenced and the human gene encoding this receptor has been localized to chromosome 5 (5q11.2-q13).
5-HT1A receptor binding sites are located primarily in limbic brain areas, notably the hypothalamus, lateral septum, cortical areas and the mesencephalic raphe nuclei. 5-HT1A receptor ligands with agonist activity possess antianxiety, antidepressant, antiaggressive, and perhaps anticraving, anticataleptic, antiemetic, and neuroprotective properties.
Potent 5-HT1A antagonist; also D4 agonist
| Chemical Name: | N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate |
| Purity: | ≥98% |
5-HT1A antagonist
| Chemical Name: | 1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazine hydrobromide |
| Purity: | ≥98% |
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
| Chemical Name: | 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate |
| Purity: | ≥98% |
Potent and selective 5-HT1A antagonist
| Chemical Name: | (S)-N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide dihydrochloride |
| Purity: | ≥98% |
β antagonist; also 5-HT1A antagonist
| Chemical Name: | 1-[(1-Methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-2-propanol hydrochloride |
| Purity: | ≥98% |
Potent 5-HT1A partial agonist and SSRI; antidepressant
| Alternate Names: | EMD 68843,SB 659746A |
| Chemical Name: | 5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamide hydrochloride |
| Purity: | ≥98% |
