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5 results for "CCR2 Small Molecules and Peptides" in Products
CCR2 Small Molecules and Peptides
CCR2, also known as CD192, is a 38 kDa 7-TM chemokine receptor that preferentially binds CCL2, CCL7, and CCL13. CCR2 is expressed by multiple hematopoietic cells, endothelial cells, fibroblasts, neurons, and smooth muscle cells. It functions as an HIV fusion co-factor and facilitates T cell recruitment during inflammation.
Highly selective CCR2 chemokine receptor antagonist
| Chemical Name: | 6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one |
| Purity: | ≥98% |
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High affinity, potent CCR2 antagonist
| Chemical Name: | 2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide |
| Purity: | ≥98% |
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CCR2b chemokine receptor antagonist
| Chemical Name: | 1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride |
| Purity: | ≥98% |
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Selective CCR2 antagonist
| Chemical Name: | N-[2-[[(3R)-1-[trans-4-Hydroxy-4-(6-methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-benzamide dimethanesulfonate |
| Purity: | ≥98% |
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Potent and selective CCR5 and CCR2 chemokine receptor antagonist
| Chemical Name: | N-[[4-[[[6,7-Dihydro-2-(4-methylphenyl)-5H-benzocyclohepten-8-yl]carbonyl]amino]phenyl]methyl]tetrahydro-N,N-dimethyl-2H-pyran-4-aminium chloride |
| Purity: | ≥98% |
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