8 results for "TrkB" in Products

TrkB Products

Members of the Trk family (TrkA, B, and C) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization cons...

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Potent TrkB agonist

Chemical Name: N,N',N''Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide
Purity: ≥98%
Potent TrkB agonist
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TrkB receptor antagonist

Chemical Name: N-[2-[[(Hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]benzo[b]thiophene-2-carboxamide
Purity: ≥98%
TrkB receptor antagonist
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TrkB agonist

Alternate Names: 7,8-DHF
Chemical Name: 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
Purity: ≥98%
TrkB agonist
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Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC

Chemical Name: N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Purity: ≥98%
Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC
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TrkB receptor antagonist

Purity: ≥95%
TrkB receptor antagonist
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TrkB and TrkC agonist; brain penetrant

Chemical Name: 2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol
Purity: ≥97%
TrkB and TrkC agonist; brain penetrant
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Selective TrkB receptor agonist; neuroprotectant

Chemical Name: N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-2-oxo-3-piperidinecarboxamide
Purity: ≥98%
Selective TrkB receptor agonist; neuroprotectant
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Potent and selective pan-Trk inhibitor; peripherally restricted

Chemical Name: N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide
Purity: ≥98%
Potent and selective pan-Trk inhibitor; peripherally restricted
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