APAF-1: Products

APAF-1, the human homolog of C. elegans CED-4, is a 130 kDa cytosolic protein that participates in the Cytochrome c-dependent activation of Caspase-3. The intrinsic Caspase activation pathway is activated by the release of mitochondrial Cytochrome c.

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Apoptosis Activator 2 

Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
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