7 results for "Autophagy-related Compounds" in Products

Autophagy-related Compounds

Autophagy is a process by which a cell breaks down macromolecules in response to starvation or stress signals. While it is closely linked with apoptosis, autophagy is primarily characterized as a catabolic mechanism by which cellular energy homeostasis is maintained, and by which cellular organelles and proteins are degraded.

Autophagy also occurs in response to similar stresses to those which induce apoptosis and several proapoptotic signals also induce autophagy - for example, ...

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Potent AMPK activator

Chemical Name: 6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
Purity: ≥98%
Potent AMPK activator
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Activator of LKB1/AMPK; antidiabetic agent

Chemical Name: N,N-Dimethylimidodicarbonimidic diamide hydrochloride
Activator of LKB1/AMPK; antidiabetic agent
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CaV1.x activator

Chemical Name: 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester
Purity: ≥98%
CaV1.x activator
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Positive regulator of autophagy

Chemical Name: 6-Bromo-N-2-propenyl-4-quinazolinamine
Purity: ≥98%
Positive regulator of autophagy
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H+-ATPase activator; activates autophagy; inactivates mTORC1 signaling

Chemical Name: N-[4-Fluoro-3-[(1-oxo-2-propen-1-yl)amino]phenyl]-1-(2-fluorophenyl)-1H-pyrazole-4-carboxamide
Purity: ≥98%
H+-ATPase activator; activates autophagy; inactivates mTORC1 signaling
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Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis

Chemical Name: N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide
Purity: ≥98%
Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis
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Inducer of autophagy via interaction of p62 and LC3

Chemical Name: 2-[[[3,4-Bis(phenylmethoxy)phenyl]methyl]amino]ethanol hydrochloride
Purity: ≥98%
Inducer of autophagy via interaction of p62 and LC3
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