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5 results for "cdk4-subfamily-inhibitors&view=expanded" in Products

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Catalog #: 4786

Potent cdk4 and cdk6 inhibitor; brain penetrant

Alternate Names:	Palbociclib
Chemical Name:	6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one isethionate salt
Purity:	≥98%

Catalog #: 2609

SETD8 inhibitor; also CDK4 inhibitor

Chemical Name:	2-Methyl-5-[(4-methylphenyl)amino]-4,7-benzothiazoledione
Purity:	≥98%

Catalog #: 7050

Dual cdk4/cdk6 inhibitor; orally bioavailable

Alternate Names:	LEE-011
Chemical Name:	7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
Purity:	≥98%

Catalog #: 6938

Selective Cdk4/6 Degrader (PROTAC®

Chemical Name:	N-[4-[4-[6-[(6-Acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]butyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide
Purity:	≥98%

Catalog #: 6921

Selective Cdk6 Degrader (PROTAC®)

Chemical Name:	N-[2-[2-[2-[2-[4-[6-[(6-Acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]ethoxy]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide
Purity:	≥98%

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