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3 results for "CEPT Cocktail Compounds Small Molecules and Peptides" in Products
CEPT Cocktail Compounds Small Molecules and Peptides
Pluripotent stem cells (PSCs) are highly sensitive to cellular stress in vitro, which presents challenges for their study and use. Small molecule ROCK (Rho-Kinase) inhibitors used as single agents, such as Y-27632 (Cat. No. 1254) and Thiazovivin (Cat. No. 3845), are known to improve viability of stem cells undergoing passaging or cryopreservation.
Chen et al. (2021), from National Center for Advancing Translational Sciences (NCATS) devised a combination of small molecules that enhances the ...
Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogenesis
| Chemical Name: | (3S)-N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-3,4-dihydro-6-methoxy-2H-1-benzopyran-3-carboxamide dihydrochloride |
| Purity: | ≥98% |
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Potent pan-caspase inhibitor
| Alternate Names: | IDN-6556,PF-03491390 |
| Chemical Name: | N-[2-(1,1-Dimethylethyl)phenyl]-2-oxoglycyl-N-[(1S)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]-L-alaninamide |
| Purity: | ≥98% |
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Integrated stress response (ISR) inhibitor
| Chemical Name: | N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] |
| Purity: | ≥98% |
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