Chemical Name: N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide
Biological ActivityGreatly enhances the efficiency of fibroblast reprogramming to generate induced pluripotent stem cells (iPSCs) when used in combination with SB 431542 (Cat. No. 1614) and PD 0325901 (Cat. No. 4192). Improves the survival of human embryonic stem cells (hESCs) upon trypsinization.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
A chemical platform for improved induction of human iPSCs.
Lin et al.
Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules.
Xu et al.
Proc.Natl.Acad.Sci. USA, 2010;107:8129
Citations for Thiazovivin
The citations listed below are publications that use Tocris products. Selected citations for Thiazovivin include:
2 Citations: Showing 1 - 2
Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells.
Nat Commun 2018;9(1):475
Live imaging reveals that the first division of differentiating human embryonic stem cells often yields asymmetric fates.
Cell Rep 2017;21(2):301
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