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3 results for "Constitutive Androstane Receptor Inverse Agonists" in Products
Constitutive Androstane Receptor Inverse Agonists
The constitutive androstane receptor (CAR) is a member of the NR1I family of nuclear receptors, along with the pregnane X receptor and vitamin D receptor. CAR is involved in the sensing and clearance of foreign toxins through the upregulation of genes involved in xenobiotic clearance, including cytochrome P450, bilirubin, and multidrug transporters.
The name 'constitutive androstane receptor' refers to the unusual, constitutively active status of this receptor when not occupied by a ...
| Chemical Name: | N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide |
| Purity: | ≥98% |
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| Chemical Name: | 6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime |
| Purity: | ≥98% |
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| Alternate Names: | CLT |
| Chemical Name: | 1-(2-Chloro-α,α-diphenylbenzyl)imidazole |
| Purity: | ≥98% |
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