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37 results for "cul2-rbx1-complex&view=expanded" in Products

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Recombinant Human CUL2/RBX1 Neddylated Complex Protein, CF

Catalog #: E3-421
Citations (1)
Product Documents

His-tag

Reactivity: Human
Source: Sf 21 (baculovirus)
Accession #: Q13617.2 (CUL2), P62877.1 (RBX1)
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes

Recombinant Human CUL2/RBX1 Complex Protein, CF

Catalog #: E3-420
Citations (2)
Product Documents
Reactivity: Human
Source: Sf 21 (baculovirus)
Accession #: Q13617.2 (CUL2), P62877.1 (RBX1)
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes

Recombinant Human Elongin B/Elongin C/VHL/CUL2/RBX1, CF

Catalog #: E3-655
(1)
Citations (2)
Product Documents
Reactivity: Human
Source: Sf 21 (baculovirus)
Accession #: P40337.2, Q15370.1, Q15369.1, Q13617.2, P62877.1
Applications: Bioactivity
Recombinant Human Elongin B/Elongin C/VHL/CUL2/RBX1 SDS-PAGE

dTAGV-1

Catalog #: 6914
(2)
Citations (92)
Product Documents

Potent and selective degrader of mutant FKBP12F36V fusion proteins

Chemical Name: (R)-3-(3,4-Dimethoxyphenyl)-1-(2-(2-((7-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-7-oxoheptyl)amino)-2-oxoethoxy)phenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate trifluoroacetate
Purity: ≥98%
Potent and selective degrader of mutant FKBP12F36V fusion proteins

dTAGV-1-NEG

Catalog #: 6915
(1)
Citations (14)
Product Documents

Negative control for dTAGV-1 (Cat. No. 6914)

Chemical Name: (R)-3-(3,4-Dimethoxyphenyl)-1-(2-(2-((7-(((S)-1-((2R,4S)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-7-oxoheptyl)amino)-2-oxoethoxy)phenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate
Purity: ≥98%
Negative control for dTAGV-1 (Cat. No. 6914)

xStAx-VHLL

Catalog #: 7298
Product Documents

Selective peptide-based β-catenin Degrader (PROTAC®)

Purity: ≥95%
Selective peptide-based β-catenin Degrader (PROTAC®)

VH 298

Catalog #: 6156
Citations (10)
Product Documents

High-affinity inhibitor of VHL

Chemical Name: (2S,4R)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98%
High-affinity inhibitor of VHL

VH 032 amide-alkylC2-amine

Catalog #: 6852
Product Documents

VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names: (S,R,S)-AHPC-C2-NH2
Chemical Name: (2S,4R)-1-((S)-2-(3-Aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity: ≥95%
VHL ligand with alkyl linker and terminal amine for onward chemistry

VH 032 amide-alkylC2-acid

Catalog #: 7106
Product Documents

VHL ligand with alkyl linker and terminal acid for onward chemistry

Alternate Names: (S,R,S)-AHPC-C2-COOH
Chemical Name: 4-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid
Purity: ≥95%
VHL ligand with alkyl linker and terminal acid for onward chemistry

ARCC 4

Catalog #: 7254
Citations (7)
Product Documents

Potent and selective androgen receptor Degrader (PROTAC®)

Chemical Name: (2S,4R)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98%
Potent and selective androgen receptor PROTAC®
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