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6 results for "Focal Adhesion Kinase Inhibitors" in Products
Focal Adhesion Kinase Inhibitors
Focal adhesion kinase (FAK), a non-receptor tyrosine kinase, is the first intracellular step in the signal transduction cascade initiated by the attachment of an integrin to the extracellular matrix at points known as focal adhesions. Therefore, FAK plays a key role in cellular migration and motility.
FAK has 3 functional domains: a focal adhesion targeting domain (FAT), a catalytic domain and a FERM domain, which mediates interactions with the cytoplasmic domains of integrins and growth ...
| Chemical Name: | 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone |
| Purity: | ≥98% |
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| Alternate Names: | Y15,NSC 677249 |
| Chemical Name: | 1,2,4,5-Benzenetetramine tetrahydrochloride |
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| Chemical Name: | N-Methyl-N-[2-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide |
| Purity: | ≥98% |
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| Chemical Name: | 2-[[2-[[2-Methoxy-4-(4-morpholinyl)phenyl]amino]-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide |
| Purity: | ≥98% |
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| Chemical Name: | N-Methyl-4-[[4-[[[3-[methyl(methylsulfonyl)amino]-2-pyrazinyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]benzamide |
| Purity: | ≥98% |
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| Chemical Name: | 2-[[5-Chloro-2-[[3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl]amino]-4-pyridinyl]amino]-N-methoxybenzamide |
| Purity: | ≥98% |
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