5 results for "GABA-B Receptor Agonists" in Products

GABA-B Receptor Agonists

GABAB receptors are GPCRs composed of seven transmembrane domains and a large extracellular N-terminal, and are responsible for mediating the inhibitory effects of GABA, alongside ionotropic GABAA and GABAA receptors. They are composed of 850 - 960 amino acids, and are most similar in structure to metabotropic glutamate receptors (mGluRs).

These receptors are heterodimers of GABAB1 and GABAB2 subunits. The GABAB1 subunit hosts the binding site for GABA and other ligands, while the GABAB2...

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Endogenous agonist

Chemical Name: γ-Aminobutyric acid
Endogenous agonist
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Selective GABAB agonist; active enantiomer of (RS)-Baclofen (Cat. No. 0417)

Alternate Names: STX 209
Chemical Name: (R)-4-Amino-3-(4-chlorophenyl)butanoic acid
Purity: ≥99%
Selective GABAB agonist; active enantiomer of (RS)-Baclofen (Cat. No. 0417)
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Caged GABA; inhibits neural activity

Alternate Names: RuBi-GABA-PMe3
Chemical Name: (bis(2,2'-Bipyridine-N,N')trimethylphosphine)-4-aminobutyric acid ruthenium complex sodium hexafluorophosphate salt
Caged GABA; inhibits neural activity
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Highly potent GABAB agonist; also GABAA-ρ antagonist

Alternate Names: CGP 35024
Chemical Name: 3-Aminopropyl(methyl)phosphinic acid
Highly potent GABAB agonist; also GABAA-ρ antagonist
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Selective GABAB agonist

Chemical Name: (RS)-4-Amino-3-(4-chlorophenyl)butanoic acid
Purity: ≥99%
Selective GABAB agonist
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