11 results for "GLP-1R Small Molecules and Peptides" in Products

GLP-1R Small Molecules and Peptides

GLP-1 R (Glucagon-like Peptide 1 Receptor) is a class B, G protein-linked, seven transmembrane domain protein that is expressed in pancreas, lung, heart, kidney, hypothalamus, and stomach. It is a receptor for Glucagon-like Peptide, a regulator of insulin secretion by pancreatic beta cells. Drugs that target GLP-1 R are of great interest for diabet...

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GSDMD (Gasdermin D) agonist, activator of pyroptosis, also GLP-1R agonist

Chemical Name: 6,7-Dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-2-quinoxalinamine
Purity: ≥98%
GSDMD (Gasdermin D) agonist, activator of pyroptosis, also GLP-1R agonist
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Potent GLP-1 receptor agonist

Alternate Names: Exenatide,AC 2993
Purity: ≥95%
Potent GLP-1 receptor agonist
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Negative allosteric modulator of glucagon and GLP-1 receptors

Chemical Name: 4-[[(4-Cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2H-tetrazol-5-ylbenzamide
Purity: ≥98%
Negative allosteric modulator of glucagon and GLP-1 receptors
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Potent GLP-1 receptor antagonist

Purity: ≥95%
Potent GLP-1 receptor antagonist
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Endogenous bioactive GLP-1 receptor ligand

Purity: ≥95%
Endogenous bioactive GLP-1 receptor ligand
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Highly potent, long-acting GLP-1 receptor agonist

Alternate Names: NN2211
Purity: ≥95%
Highly potent, long-acting GLP-1 receptor agonist
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Potent insulinotropic peptide

Alternate Names: GLP-1 (7-36) amide
Purity: ≥95%
Potent insulinotropic peptide
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Metabolite of GLP-1-(7-36) (Cat. No. 2082)

Alternate Names: Glucagon-like peptide 1 (9-36) amide
Purity: ≥95%
Metabolite of GLP-1-(7-36) (Cat. No. 2082)
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Endogenous pancreatic peptide

Alternate Names: GLP-1 (1-37) amide
Purity: ≥95%
Endogenous pancreatic peptide
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Positive allosteric modulator of GLP-1 receptors

Chemical Name: 2-(Ethylsulfinyl)-4-[3-(phenylmethoxy)phenyl]-6-(trifluoromethyl)pyrimidine
Purity: ≥98%
Positive allosteric modulator of GLP-1 receptors
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Non-competitive GLP-1 antagonist; orally bioavailable and brain penetrant

Chemical Name: 7-(4-Chlorophenyl)-5,8-dihydro-1,3-dimethyl-5,5-bis(trifluoromethyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione
Purity: ≥98%
Non-competitive GLP-1 antagonist; orally bioavailable and brain penetrant
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