8 results for "Histone Deacetylase 2/HDAC2 Small Molecules and Peptides" in Products
Histone Deacetylase 2/HDAC2 Small Molecules and Peptides
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly conserved from yeast to human.
Highly potent and selective HDAC2 inhibitor
| Chemical Name: | Ethyl N-[4-oxo-4-[(2-phenylethyl)amino]butyl]carbamate |
| Purity: | ≥98% |
Potent class I and IIb HDAC inhibitor
| Chemical Name: | 5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide |
| Purity: | ≥98% |
Histone deacetylase inhibitor
| Alternate Names: | VPA,Sodium Valproate |
| Chemical Name: | Sodium 2-propylpentanoate |
Potent and selective class I histone deacetylase inhibitor; antitumor
| Alternate Names: | Depsipeptide,FR 901228,Romidepsin |
| Chemical Name: | Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl], cyclic (3-5) disulfide |
| Purity: | ≥98% |
Class I and II HDAC inhibitor
| Alternate Names: | Vorinostat |
| Chemical Name: | N-Hydroxy-N'-phenyloctanediamide |
| Purity: | ≥98% |
Histone deacetylase inhibitor
| Alternate Names: | 4-PB,Sodium phenylbutyrate |
| Chemical Name: | 4-Phenylbutyric acid, sodium salt |
| Purity: | ≥98% |
Pan-histone deacetylase inhibitor
| Chemical Name: | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Purity: | ≥98% |
HDAC (Class I) inhibitor
| Alternate Names: | entinostat,SNDX 275 |
| Chemical Name: | (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate |
| Purity: | ≥98% |
