6 results for "Integrin alpha 4 beta 7/LPAM-1 Small Molecules and Peptides" in Products

Integrin alpha 4 beta 7/LPAM-1 Small Molecules and Peptides

Integrin alpha 4 beta 7 (LPAM-1) is an integrin family adhesion receptor that shares subunits with VLA4 and the E-cadherin receptor. It is the non-covalent heterodimer of alpha 4/CD49d and beta 7 transmembrane subunits. Motifs within a4b7 bind to metal ions and regulate cell adhesion functions. a4b7 binds the mucosal addressin MAdCAM-1, as well as ...

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Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs

Chemical Name: N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine sodium salt
Purity: ≥98%
Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs
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Highly potent and selective inhibitor of integrin α4β1 (VLA-4)

Chemical Name: (2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]butanoic acid
Purity: ≥98%
Highly potent and selective inhibitor of integrin α4β1 (VLA-4)
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Selective α4β1 (VLA-4) inhibitor

Purity: ≥95%
Selective α4β1 (VLA-4) inhibitor
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Potent integrin α4β7 and α4β1 (VLA-4) antagonist; orally bioavailable

Chemical Name: (αS)-α-[(2,6-Dichlorobenzoyl)amino]-2',6'-dimethoxy[1,1'-biphenyl]-4-propanoic acid
Purity: ≥98%
Potent integrin α4β7 and α4β1 (VLA-4) antagonist; orally bioavailable
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α4β1 (VLA-4) antagonist

Chemical Name: 1-[[(3S)-4-[2-[4-[[[(2-Methylphenyl)amino]carbonyl]amino]phenyl]acety]l-3-morpholinyl]carbonyl]-4-piperidinediacetic acid
Purity: ≥98%
α4β1 (VLA-4) antagonist
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α4β1 (VLA-4) ligand

Purity: ≥95%
α4β1 (VLA-4) ligand
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